Characteristics in Post Covid-19 Patients
- Conditions
- Coronavirus Infection
- Interventions
- Other: Exercise
- Registration Number
- NCT04514705
- Lead Sponsor
- Universidade Metodista de Piracicaba
- Brief Summary
To evaluate pulmonary changes and the results of a cardiopulmonary rehabilitation protocol (CPRP) in patients after SARS-VOC-2 infection. Clinical trial type study to be conducted between 2020 and 2024 involving clinical-functional cardiopulmonary imaging and blood transcriptome profile: before CPRP (T1), 2 months after CPRP (T2) and 1 year later (T3). Expected results: a) clinical, image and transcriptome changes; b) clinical-functional improvement after CPRP.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 20
- With confirmed diagnosis for SARS-COV-2.
- With any type of simultaneous pneumopathy.
- Patients with autoimmune disease
- People with simultaneous infectious diseases
- Pregnant women
- With degenerative diseases of the nervous system or musculoskeletal system
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Intervention Group Exercise The exercises performed will attend the musculoskeletal dimension of the body, which includes the muscular strength / endurance indexes, which is part of the functional-motor dimension of physical fitness related to health. The protocol will be applied in the form of sessions lasting approximately 50 minutes, performed three times a week on alternate days, for a period of 6 weeks, totaling 20 sessions. For aerobic exercises, a treadmill will be used and for anaerobic exercises, four exercises involving muscle mobility / strength in upper and lower limbs will be performed at weight training station.
- Primary Outcome Measures
Name Time Method Characteristics of lung post treatment in 3 days In the supine position, the patient will perform deep inspiration followed by momentary apnea inside the high resolution scanner to capture cross-sectional images of the chest with smaller cuts than 1mm of collimation which helped in the detection of even small lesions.
Respiratory muscle strength post treatment in 3 days Respiratory muscle strength will be assessed using the digital manovacuometer. The measurement will be performed as follows the patient will be asked to empty the lungs to the residual volume and then perform an inhalation until the total lung capacity.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Universidade do Estado do Pará
🇧🇷Belém, Pará, Brazil