ACTRN12620000230954尚未招募4 期
Comparison of intravenous Amoxicillin/Clavulanate to Piperacillin/Tazobactam for the empiric treatment of moderate diabetic foot infections in adults: A pragmatic, non-inferiority, randomised trial
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 484
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •18 years of age and older
- •Diabetes mellitus (type 1 or 2)
- •Moderate (Grade 3) diabetic foot infection (IDSA grading)
排除标准
- •Severe (Grade 4) infection
- •Pregnant women
- •Documented allergy to penicillin
- •Received greater than 24hrs of trial drug prior to enrolment
- •Eligible for targeted therapy (i.e. have deep specimen bacteriological culture results).
- •Severe renal impairment (eGFR <10mL/min) or requiring renal replacement therapy
- •Unable to give consent for trial
研究者
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