Bacterial translocation, and intestinal permeability in patients undergoing open or laparoscopic total colectomy.- open, right side or left side first laparoscopically
Recruiting
- Conditions
- Bacterial translocation, total colectomy, proctocolectomy, intestinal permeability, devascularisation, laparoscopic colectomy.Bacteriele translocatie, proctocolectomie, intestinale permeabiliteit, devascularisatie, laparoscopie
- Registration Number
- NL-OMON22017
- Lead Sponsor
- Academic Medical Centre (AMC)department of SurgeryAmsterdam
- Brief Summary
n/a
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Age >18 years;
2. Patients planned for laparoscopic total colectomy for inflammatory bowel diseases or familial adenomatous polyposis or patients undergoing subtotal colectomy;
3. Informed consent.
Exclusion Criteria
1. Antibiotics within a week prior to surgery (perioperative antibiotics are allowed);
2. Use of probiotic products 4 weeks before or during the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Intestinal permeability;<br>2. Amount of bacterial translocation<br>
- Secondary Outcome Measures
Name Time Method