跳至主要内容
临床试验/NCT05226403
NCT05226403已完成不适用

Descriptive Study of Clinical and Pulmonary Ultrasound Signs of Acute Respiratory Infections Associated With COVID-19 in Primary Care

Geprovas1 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2020年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
38
试验地点
1
主要终点
Ultrasound Signs

研究概览

简要总结

COVID-19 infection are characterized by fever and signs of acute respiratory infection. A worsening of respiratory symptoms that can lead to respiratory failure. The decompensation can then be brutal and require rapid recourse to respiratory assistance. The contribution of clinical examination (auscultation and monitoring of oxygen saturation in particular) remains unsatisfactory in predicting an unfavorable course. The interest of pulmonary ultrasound is known in the management of pulmonary infections. However, estimating the severity of lung damage at an early stage could be of great help in monitoring and caring for patients. Ultrasound could meet this need in general practice, the chest scanner is often unavailable in these situations.

Ultrasound signs are associated with severe forms. The contribution of pulmonary ultrasound seems particularly interesting in the context of the reassessment of patients during the worsening phase of symptoms (D5-D10).

Estimate the prevalence of ultrasound signs in patients with an acute respiratory infection suspected or confirmed to be COVID-19, at the time of the worsening phase (between D5 and D10 of the onset of symptoms).

The prevalence of ultrasound lung lesions under COVID-19 may be essential to consider the development of the ultrasound tool in primary care. Indeed, if the contribution of ultrasound is now recognized in intensive care or emergency, its place in general medicine still raises questions.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients over 18 years of age with :
  • a clinical symptomatology suggesting an acute respiratory infection linked to COVID-19 defined by the following two categories of symptoms:
  • Sudden fever (or a feeling of fever)
  • Respiratory signs (cough, dyspnea, chest tightness) Or
  • an acute respiratory infection confirmed to COVID-19 by the result of RT-PCR screening tests.
  • And presenting, at the time of inclusion between the 5th and 10th day of infection, one of the respiratory signs of severity felt:
  • Dyspnea, shortness of breath or difficulty in breathing
  • Chest pain or tightness

排除标准

  • The presence of a severe form during the initial consultation. A severe form is defined by the presence of the following signs:
  • Polypnea> 22 / min
  • systolic BP <90 mmHg
  • Sp02 <90%
  • Altered consciousness, confusion, drowsiness
  • Dehydration
  • Alteration of the general condition in the elderly
  • The presence of acute respiratory signs clearly having a cause other than a COVID-19 infection.

结局指标

主要结局

Ultrasound Signs

时间窗: Between day 5 and day 10 of infection

Frequency of the presence of at least one ultrasound sign in the subjects included

次要结局

  • Evolution and complication(Day 14 of infection)
  • Clinical Signs(Day 5 and Day 10)
  • Ultrasound signs(Between day 5 and day 10)

研究者

发起方
Geprovas
申办方类型
Network
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验