Corneal Densitometry Changes With Adenoviral Keratoconjunctivitis Sub Epithelial Infiltrates
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- changes of corneal densitometry
研究概览
简要总结
Adenoviral Sub epithelial infiltrates (SEI) affect ocular function.They lead to reduced vision, photophobia, glare, halos, and foreign body sensation.
详细描述
first group of patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.S econd group underwent transepithelial PTK for subepithelial infiltrates. Baseline and post-treatment full ophthalmic examination was done.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adenoviral SEI
排除标准
- •Other corneal diseases
研究组 & 干预措施
Tacrolimus
Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.
干预措施: Tacrolimus ointment (Drug)
Phototherapeutic Keratectomy
Patients underwent transepithelial PTK for subepithelial infiltrates.
干预措施: phototherapeutic keratectomy (Procedure)
结局指标
主要结局
changes of corneal densitometry
时间窗: 6 months
Sub epithelial infiltrates was examined with the densitometry programme of the Pentacam (Fa. Oculus,Weimar, Germany)
次要结局
未报告次要终点
研究者
Tarek Roshdy mohamed Mahgoub ELhamaky
Lecturer
Benha University