Ginger effect on pain in knee osteoarthritis
- Conditions
- Knee osteoarthritis.Primary gonarthrosis, bilateral
- Registration Number
- IRCT201111088034N1
- Lead Sponsor
- Tehran University of medical sciences, Vice chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 140
Inclusion criteria; knee pain and osteophyte in knee radiography; and at least one criterion of the three following criteria: 50 years age; Morning stiffness of less than 30 minutes; Crepitus in motion. Exclusion criteria: The history of rheumatoid arthritis, gout, chondrocalcinosis; severe and advanced cardiovascular disease class 4; proven malignancy; there is significant liver disease (esophageal varices and bleeding, encephalopathy, ascites); severe renal disease (creatinine greater than 3 mg dL); pregnancy and lactation; received intra-articular drug in former three months (or wait until this time period be spent); Glucosamine or Piascledine receive more than 2 weeks during the past six months; concomitant hip osteoarthritis
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Knee pain. Timepoint: 6 week. Method of measurement: VAS, Lequensnes Pain Index Of Severity For OA Of The Knee, VOMAC.
- Secondary Outcome Measures
Name Time Method Joint crepitus. Timepoint: 6 month. Method of measurement: physical exam.;Patient global assessment. Timepoint: Each 6 weeks. Method of measurement: Interview.;Physician global assessment. Timepoint: Each 6 weeks. Method of measurement: Questionnaire.;Drug side effect. Timepoint: Each 6 weeks. Method of measurement: Interview.