NL-OMON52291
Recruiting
Not Applicable
Atypical parkinsonism: Early diagnosis with quantitative MRI - APqMRI
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atypical parkinsonism
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 55
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Patients who present at the outpatient clinic of the department of neurology
- •with symptoms consistent with degenerative parkinsonism.
- •\- For possible PD patients: Diagnosis of Parkinson\*s disease is unclear and an
- •atypical form of parkinsonism is suspected.
- •\- For near\-certain PD patients: Patients for whom Parkinson\*s disease is highly
- •\- At least 50 years old
- •\- Signed informed consent.
- •Healthy volunteers:
- •\- Healthy subject (defined as a volunteer without and signs or symptoms of
- •\- At least 50 years old and not older than 75
Exclusion Criteria
- •\- Patients with parkinsonism symptoms caused by medication or essential
- •In addition, both patients and healthy volunteers are excluded if they meet any
- •of the following criteria:
- •\- a history of another neurodegenerative disease.
- •\- History of significant intracranial disease
- •\- Contra\-indication to an MRI exam
- •\- Metal implants
- •\- Women who are pregnant or lactating
- •\- Having any physical or mental status that interferes with the informed
- •consent procedure
Outcomes
Primary Outcomes
Not specified
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