Atypical parkinsonism: Early diagnosis with quantitative MRI - APqMRI

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 55 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•- Patients who present at the outpatient clinic of the department of neurology
•with symptoms consistent with degenerative parkinsonism.
•- For possible PD patients: Diagnosis of Parkinson*s disease is unclear and an
•atypical form of parkinsonism is suspected.
•- For near-certain PD patients: Patients for whom Parkinson*s disease is highly
•- At least 50 years old
•- Signed informed consent.
•Healthy volunteers:
•- Healthy subject (defined as a volunteer without and signs or symptoms of
•- At least 50 years old and not older than 75
•- Signed informed consent

•- Patients with parkinsonism symptoms caused by medication or essential
•In addition, both patients and healthy volunteers are excluded if they meet any
•of the following criteria:
•- a history of another neurodegenerative disease.
•- History of significant intracranial disease
•- Contra-indication to an MRI exam
•- Metal implants
•- Women who are pregnant or lactating
•- Having any physical or mental status that interferes with the informed
•consent procedure

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