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Clinical Trials/CTRI/2025/02/081308
CTRI/2025/02/081308
Not yet recruiting
Phase 2

Effectiveness of Electro-Acupuncture as an Alternative Therapy among Oral Sub-Mucous Fibrosis patients- A Randomised Controlled Trial

Dr S Priyanka1 site in 1 country50 target enrollmentStarted: May 1, 2025Last updated:

Overview

Phase
Phase 2
Status
Not yet recruiting
Sponsor
Dr S Priyanka
Enrollment
50
Locations
1
Primary Endpoint
1) To evaluate pain score 0-10, mouth opening and burning sensation of mouth score 0-10

Overview

Brief Summary

This study is a randomised controlled trial comparing the effectiveness of electro-acupuncture therapy in reducing pain, improving mouth opening and reducing burning sensation among 50 oral sub-mucous fibrosis patients along with conventional treatment in India. 

The primary outcome measures will be:

  1. To evaluate the effectiveness of electro-acupuncture therapy in reducing pain, improving mouth opening and reducing burning sensation of mouth in patients with grade I to grade III oral sub-mucous fibrosis along with conventional treatment.

2. To compare the effect of electro-acupuncture intervention along  with conventional treatment and only conventional treatment.

The secondary outcomes will be:

1. To compare the effectiveness of pain and mouth opening between Grade I, Grade II and Grade III oral sub-mucous fibrosis patients in experimental and control group.

  1. To assess the patient acceptance and satisfaction of electro-acupuncture as an alternate therapy.

NULL HYPOTHESIS:

1. There is NO difference in pain, mouth opening and  burning sensation amongst patients who receive electro-acupuncture therapy along with conventional treatment for Grade I to Grade III Oral Sub-Mucous Fibrosis.

  1. Electro-acupuncture therapy along with conventional treatment is NOT effective in comparison with conventional treatment in patients with Grade I to Grade III Oral Sub-Mucous Fibrosis.

  2. There is NO significant difference in pain and mouth opening among Grade I, Grade II, and Grade III Oral Sub-Mucous Fibrosis patients between the experimental and control groups.

  3. Electro-acupuncture does NOT lead to significant levels of patient acceptance and satisfaction in the treatment of Grade I to Grade III oral sub-mucous fibrosis patients.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 55.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Oral sub-mucous fibrosis patients suffer from severe burning sensations, dry mouth, pain, taste disorders, tongue mobility limitations less than 35mm, trismus, dysphagia, and altered tone.

Exclusion Criteria

  • A history of bleeding disorder, acupuncture treatment, pregnant or lactating women and subjects with wounds/ tumour in the area of needling.

Outcomes

Primary Outcomes

1) To evaluate pain score 0-10, mouth opening and burning sensation of mouth score 0-10

Time Frame: Every week for 1month and at the end of 2nd month

2) To compare the effect of electro-acupuncture intervention along with conventional treatment and only conventional treatment.

Time Frame: Every week for 1month and at the end of 2nd month

Secondary Outcomes

  • To compare the effectiveness of pain and mouth opening between Grade I, Grade II and Grade III oral sub-mucous fibrosis patients in experimental and control group.(2months)
  • To assess the patient acceptance score 0-10 and satisfaction score 0-10 of electro-acupuncture as an alternate therapy.(At the end of 1st month)

Investigators

Sponsor
Dr S Priyanka
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr S Priyanka

Shri Dharmasthala Manjunatheshwara College Of Dental Sciences And Hospital

Study Sites (1)

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