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临床试验/NCT07147777
NCT07147777已完成不适用

Effect of Physical Activity During Pregnancy on Uterine Artery Blood Flow, Fetal Heart Rate and Fetal Birth Weight

Antalya Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 159 人开始时间: 2025年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
159
试验地点
1
主要终点
Resistance index measurement

研究概览

简要总结

This study investigates the relationship between physical activity levels and fetal health in the third trimester of pregnancy. Using the PPAQ and daily step counts, researchers will measure physical activity and examine its effects on uterine blood flow, fetal heart rate, and birth weight. The study hypothesizes that both inactivity and excessive activity may negatively impact fetal health. By focusing on overall activity levels rather than acute effects, this research aims to provide new insights to inform recommendations for a healthy pregnancy.

详细描述

Urbanization, rising living standards, and the comfort afforded by technological advances, characteristic of our age, are leading to the prevalence of physical inactivity. The potential effects of this on maternal and fetal health, especially during a sensitive period like pregnancy, pose a critical need for scientific research. The third trimester of pregnancy is a critical period during which fetal growth and development occur rapidly, and investigating the effects of physical inactivity on the fetus is of great importance.

In this study, physical activity levels during pregnancy will be determined using the Pregnancy Physical Activity Questionnaire (PPAQ) and daily step count. Fetal health parameters will include uterine blood flow markers (Resistance Index (RI), Systolic/Diastolic (S/D) ratio), fetal heart rate, and fetal birth weight. This study aims to make significant contributions to the literature by revealing the impact of physical activity levels on fetal health parameters in third-trimester pregnancies. Research Hypothesis:

This study will examine the effects of physical activity levels on fetal health parameters within the framework of the following hypotheses:

H1 (Research Hypothesis 1): It is hypothesized that fetal health parameters will be negatively affected in pregnant women who are physically inactive during pregnancy (e.g., impaired values, low birth weight).

H0 (Null Hypothesis 1): There is no statistically significant difference in fetal health parameters between pregnant women who are physically inactive during pregnancy and those who are active.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •Singleton pregnancy
  • •≥28 gestational weeks (confirmed by ultrasound)
  • •Willing and able to participate; provides written informed consent
  • •Owns a mobile phone capable of step-count data collection

排除标准

  • •Multiple pregnancy
  • •History of miscarriage in previous pregnancies
  • •Chronic systemic disease (e.g., diabetes, hypertension, thyroid disease)
  • •Detection of fetal anomalies
  • •Drug or substance abuse
  • •Current cigarette smoking
  • •Serious psychiatric illness

研究组 & 干预措施

Overactive group

Pregnant women will be divided into three categories based on the distribution of their PPAQ scores: the bottom 33% (inactive group), the middle 33% (moderately active group), and the top 33% (overactive group).

Inactive group

Pregnant women will be divided into three categories based on the distribution of their PPAQ scores: the bottom 33% (inactive group), the middle 33% (moderately active group), and the top 33% (overactive group).

Moderately active group

Pregnant women will be divided into three categories based on the distribution of their PPAQ scores: the bottom 33% (inactive group), the middle 33% (moderately active group), and the top 33% (overactive group).

结局指标

主要结局

Resistance index measurement

时间窗: 28-40 weeks of gestation

Systolic speed minus diastolic speed divided by systolic speed

Systolic-diastolic ratio measurement

时间窗: 28-40 weeks of gestation

Systolic value divided by diastolic value on ultrasound

Fetal hearth rate measurement

时间窗: 28-40 weeks of gestation

Fetal heart rate measured during sonographic obstetric evaluation of the fetus

次要结局

  • Baby's birth weight measurement(Day of delivery)

研究者

发起方
Antalya Training and Research Hospital
申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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