Santeon-CAP study Dexamethasone in community-acquired pneumonia. - Santeon-CAP study

未提供0 个研究点目标入组 600 人开始时间: 2012年1月9日最近更新: 2019年4月30日

适应症

试验速览

暂无简介。

•Patients aged 18 to 100 years with a community-acquired pneumonia which requires admission.
•Criteria to determine a community-acquired pneumonia:
•-Chest radiograph showing new opacities.
•In combination with two of the following findings:
•0Production of sputum
•0Temp >38,0 °C or <36,0 °C
•0Audible abnormalities by chest examination compatible with pneumonia
•0Leukocytosis (>10.000 cells/mm3), leftward shift (>10%) or leucopenia (<4000 cells/mm3)
•0CRP > 15 mg/l (three fold higher than the upper limit of normal)
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 300
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 300

•-Immunocompromised patients:
•0Patients with a known congenital or acquired immunodeficiency.
•0Patients who received chemotherapy less than 6 weeks ago.
•0Patients who received corticosteroids in the last 6 weeks.
•0Patients who received immunosuppressive medication in the last 6 weeks (e.g. cyclosporin, cyclophosphamide, azathioprine).
•0Patients with COPD who are on systemic corticosteroids for COPD.
•-Patients who require ICU treatment.
•-Patients with tropical worm infection.
•-Patients with dexamethasone intolerance.
•-Pregnant and breastfeeding women.

发起方

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