CGF Influence on Post-operative Complications.

Not Applicable

• Conditions: Post-operative Wound Healing; CGF; Bone Loss
• Interventions: Procedure: CGF application

• Registration Number: NCT03992573
• Lead Sponsor: Medical University of Lodz

Brief Summary

The aim of the study is to evaluate the influence of CGF application into post-operative soft tissue and bone defects on post-operative complications and wound healing.

Detailed Description

The research was conducted in twenty patients with symmetric single tooth qualified to extraction. On one side of dental arch, post-operative region was field with CGF material, while on the other side it was left to normal healing. In both cases pain, swelling, alveolar osteitis, antibiotics and analgesics intake in post-operative period were evaluated in the first, fourth and seventh day after surgery. Wound healing was assessed seven and thirty days after extraction.

Study Timeline

• Study Start: 2017-10-01
• Status Verified: 2019-06
• Study First Submitted: 2019-06-18
• Study First Submitted QC: 2019-06-18
• Study First Posted: 2019-06-20
• Last Update Submitted: 2019-07-05
• Last Update Posted: 2019-07-08
• Primary Completion: 2020-03-01
• Study Completion: 2020-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• no known medical history of abnormal platelet counts,
• patients with symmetric teeth qualified for extraction,

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Exclusion Criteria

• systemic diseases,
• pregnancy,
• lactation,
• drugs known to affect the number or function of platelets,
• abnormal platelet counts

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group	CGF application	-

Primary Outcome Measures

Name	Time	Method
Intensity of pain vs. CGF application	24 hours	In order to evaluate the relationship between intensity of pain after surfery and filling the alveolus with platelet-rich plasma, , NRS (Numeric Rating Scale) pain scale is used.; NRS scale, ranges from 0 to 10; where 0 refers to no pain and 10 refers to most severe pain.

Secondary Outcome Measures

Name	Time	Method
Occurrence of swelling	24 hours	The presence of swelling was evaluated using zero one system.

Trial Locations

Locations (1)

Department of Oral Surgery; 🇵🇱 Lodz, Poland