The Influence of Concentrated Growth Factors (CGF) Application on Post-operative Complications.
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Intensity of pain vs. CGF application
研究概览
简要总结
The aim of the study is to evaluate the influence of CGF application into post-operative soft tissue and bone defects on post-operative complications and wound healing.
详细描述
The research was conducted in twenty patients with symmetric single tooth qualified to extraction. On one side of dental arch, post-operative region was field with CGF material, while on the other side it was left to normal healing. In both cases pain, swelling, alveolar osteitis, antibiotics and analgesics intake in post-operative period were evaluated in the first, fourth and seventh day after surgery. Wound healing was assessed seven and thirty days after extraction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •no known medical history of abnormal platelet counts,
- •patients with symmetric teeth qualified for extraction,
排除标准
- •systemic diseases,
- •pregnancy,
- •lactation,
- •drugs known to affect the number or function of platelets,
- •abnormal platelet counts
研究组 & 干预措施
Study group
干预措施: CGF application (Procedure)
Control group
结局指标
主要结局
Intensity of pain vs. CGF application
时间窗: 24 hours
In order to evaluate the relationship between intensity of pain after surfery and filling the alveolus with platelet-rich plasma, , NRS (Numeric Rating Scale) pain scale is used. NRS scale, ranges from 0 to 10; where 0 refers to no pain and 10 refers to most severe pain.
次要结局
- Occurrence of swelling(24 hours)