ow level laser effect on improving the blood flow in diabetic foot ulcers
Not Applicable
- Conditions
- Diabet Melitus Type 2.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT2014051717723N1
- Lead Sponsor
- Tarbiat Modares University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Inclusion:
1. Diabetic patients with ischemic diabetic foot ulcers (of both sexes) aged 40 to 60 years
2. 32> BMI> 25
3.Wagner grade 2 diabetic ulcers and ulcer size larger than the standard 2 cm below the ankle area
4. Mild to moderate neuropathic diabetic foot screening table (UK)
5. 0.50 ? Ankle Brachial Index < 0.9
6. HbA1c < 8
7. Non-smoking
8. No signs of wound infection
10. No Having kidney disease(serum creatinine level less than 2 mg / dL )
11. No Having body fracture occurred recently.
12. No Having skin diseases
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ankle Brachial Index. Timepoint: session 1 and 12. Method of measurement: Digital Manometer.;Oxygen saturation of peripheral blood. Timepoint: session 1 , 6,12. Method of measurement: Pulse oxymeter.;Wouns surface area. Timepoint: session 1 , 6,12. Method of measurement: Imaging.;Nitric Oxide. Timepoint: session 1 and 12. Method of measurement: biochemical analysis.;HIF-1a. Timepoint: session 1 and 12. Method of measurement: biochemical analysis.;Vascular Endothelial Growth Factor. Timepoint: session 1 and 12. Method of measurement: biochemical analysis.;Vascular Endothelial Growth Factor-Receptor 2. Timepoint: session 1 and 12. Method of measurement: biochemical analysis.
- Secondary Outcome Measures
Name Time Method Assessment of physical activity and pain. Timepoint: Start and end of study. Method of measurement: standard Questionnaire SF-36.