NCT00791323已完成4 期
Efficacy of Ketorolac 0.4% in Prostaglandin Suppression
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Allergan
- 入组人数
- 9
- 主要终点
- Mean Prostaglandin E2 (PGE2) Aqueous Humor Levels
研究概览
简要总结
A pilot study to evaluate the extent of PGE2 inhibition (mean aqueous values) by Ketorolac 0.04% following peripheral iridotomy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled to undergo phakic IOL implantation
排除标准
- •History of intraocular surgery in the operative eye
研究组 & 干预措施
1
Active Comparator
Ketorolac 0.4%
干预措施: Ketorolac 0.4% (Drug)
2
Active Comparator
Mineral Oil Emollient
干预措施: Lubricating Eye Drop (Drug)
结局指标
主要结局
Mean Prostaglandin E2 (PGE2) Aqueous Humor Levels
时间窗: Day 3
The mean level of PGE2 (a naturally occurring prostaglandin E2 in the eye that can cause inflammation and other complications) in the aqueous humor (the thin, watery fluid in the eye) 2 days following peripheral iridotomy (ocular surgery).
次要结局
未报告次要终点
研究者
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