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Clinical Trials/NCT05624814
NCT05624814
Not yet recruiting
Not Applicable

Long-term Psychological Evaluation of Patients With Implanted Spinal Cord Stimulator

University Magna Graecia1 site in 1 country60 target enrollmentJanuary 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Psychological Disability
Sponsor
University Magna Graecia
Enrollment
60
Locations
1
Primary Endpoint
Global Cognitive Functioning - Montreal Cognitive Assessment
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

Spinal cord stimulation (SCS) is a therapeutic option for patients with chronic low back pain (CLBP) syndrome, when pharmacological, psychological, physical and occupational therapies or surgery fail to reduce symptoms. CLBP is a common disease with several negative consequences on the quality of life, work and activity ability and increased costs to the health-care system. We have therefore designed this observational study to assess global cognitive functioning in three different groups of patients: patients with chronic pain undergoing intervention (experimental group), patients with chronic pain following traditional therapies (comparison group) and healthy participants matched for age and schooling (healthy subjects).

A neuropsychological assessment battery designed to assess global cognitive functioning, behavioral symptomatology, metacognition, quality of life, interoception, pain perception, self-efficacy, and coping styles will be conducted.

Registry
clinicaltrials.gov
Start Date
January 1, 2023
End Date
December 31, 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Magna Graecia
Responsible Party
Principal Investigator
Principal Investigator

Federico Longhini

Director of the Intensive Care and Anesthesia Department

University Magna Graecia

Eligibility Criteria

Inclusion Criteria

  • age greater than 18 years
  • presence of chronic pain treated with spinal cord stimulation (Experimental Group)
  • presence of chronic pain receiving standard therapies (Comparison Group)
  • healthy participants matched for age and schooling (Control Group).

Exclusion Criteria

  • consent denied

Outcomes

Primary Outcomes

Global Cognitive Functioning - Montreal Cognitive Assessment

Time Frame: At patient's inclusion

Montreal Cognitive Assessment provides screening of global cognitive functioning; it is composed of 12 subtasks exploring: memory; visuospatial abilities assessed by a clock-drawing task and by copying of a cube; executive functions assessed by means of a brief version of the Trail Making B task, a phonemic fluency task, and a two-item verbal abstraction task; attention, concentration and working memory assessed by means of a sustained attention task (target detection using tapping), a serial subtraction task, and forward and backward span tasks for digits; language assessed by a naming task with low-familiarity animals, repetition of two syntactically complex sentences and the above-mentioned phonemic fluency task; temporal and spatial orientation.

Global Cognitive Functioning - Raven's Colored Progressive Matrices Test

Time Frame: At patient's inclusion

The Raven's Colored Progressive Matrices Test assesses abstract reasoning abilities with nonverbal material. The test consists of 36 matrices, grouped into 3 sets of increasing difficulty. Each matrix has a missing piece that the subject must choose from six alternatives available. The total score ranges from 0 to 36 and is obtained by summing the number of correct answers.

Secondary Outcomes

  • Metacognition - Multifactorial Memory Questionnaire(At patient's inclusion)
  • Metacognition - Adult Executive Functioning Inventory(At patient's inclusion)
  • Quality of life(At patient's inclusion)
  • Metacognition - Memory Assessment Clinics-Questionnaire(At patient's inclusion)
  • Behavioral Symptomatology - Beck Depression Inventory(At patient's inclusion)
  • Behavioral Symptomatology - State-Trait Anxiety Inventory(At patient's inclusion)
  • Behavioral Symptomatology - Apathy Evaluation Scale(At patient's inclusion)
  • Pain - Numeric Rating Scale(At patient's inclusion)
  • Disability - Roland Morris Disability Questionnaire(At patient's inclusion)
  • Pain and disability - Pain Catastrophizing Scale(At patient's inclusion)
  • Resilience, Perceived Self-efficacy, and Coping Styles - Brief Resilience Scale(At patient's inclusion)
  • Resilience, Perceived Self-efficacy, and Coping Styles - Pain Self-Efficacy Questionnaire(At patient's inclusion)
  • Resilience, Perceived Self-efficacy, and Coping Styles - Coping Scale(At patient's inclusion)
  • Interoception - Heartbeat Detection Task(At patient's inclusion)
  • Interoception - Self Awareness Questionnaire(At patient's inclusion)
  • Interoceptive awareness(At patient's inclusion)

Study Sites (1)

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