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Clinical Trials/NL-OMON44723
NL-OMON44723
Completed
Phase 3

A multicentre randomised controlled trial to compare the efficacy of ex-vivo oxygenated hypothermic machine perfusion with non-oxygenated hypothermic machine perfusion of kidneys from donors older than 50 years of age and donated after circulatory death. - COPE-COMPARE

niversity of Oxford0 sites93 target enrollmentTBD
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ConditionsEndstage renal failureRenal insufficiency1002914910038365

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Endstage renal failure
Sponsor
niversity of Oxford
Enrollment
93
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Eligibility Criteria

Inclusion Criteria

  • •For the donor and the donor kidney:
  • •\- Maastricht category III DCD donors (donors who died after circulatory arrest in a controlled setting)
  • •\- Aged 50 years or older;For the recipient:
  • •\- At least 18 years of age
  • •\- Listed for renal trasplantation due to end stage renal disease on the ET or NHSBT renal waiting list within one of the participating centres
  • •\- Willingness to comply with the protocol procedures for the duration of the study, including scheduled follow\-up visits and examinations

Exclusion Criteria

  • •For the donor and the donor kidney:
  • •\- Kidney deemed untransplantable by the retrieval surgeon. The contralateral kidney will also not be randomised as the trial is designed as a paired trial;For the recipient:
  • •\- Scheduled to undergo multi\-organ transplantation
  • •\- Planned dual kidney transplantation

Outcomes

Primary Outcomes

Not specified

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