Effects of deep brain stimulation on eye movements
- Conditions
- eye movement disorders10029301
- Registration Number
- NL-OMON36854
- Lead Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
*Patients (age: 40 - 80) have Parkinson*s disease, essential tremor, Dystonia or Tourette Syndrom treated with DBS.
*The surgery took place at least 3 months prior to this eye movement study without complications.
Exclusion Criteria
*Patients with other disease than the above mentioned
*Intraocular disease such as macular degeneration
*Strabismus
*Deformities of the eye bulb
*Minors and incapacitated patients
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1) saccades:<br /><br>a. latency: time between the onset of the target (i.e. the point of light) and<br /><br>the beginning of the eye movement.<br /><br>b. accuracy of saccadic eye movements: final eye position over the final<br /><br>position of the point of light<br /><br><br /><br>2) smooth pursuit:<br /><br>max. speed of the eye over the speed of the point of light at 0.2 Hz & 0.4 Hz<br /><br><br /><br>3) gaze-holding functioning:<br /><br>fixation nystagmus while looking straight ahead, left, right, up and down<br /><br><br /><br>4) head impulse test:<br /><br>max. speed of the eye over the max. speed of the head in the opposite</p><br>
- Secondary Outcome Measures
Name Time Method <p>The above mentioned parameters of one subgroup will be compared with the<br /><br>parameters of another subgroup (i.e. Parkinson*s disease versus essential<br /><br>tremor, Parkinson*s disease versus dystonia)</p><br>