Effects of Daily Low-Fat Synbiotic Yogurt Consumption on Metabolic Parameters, Inflammatory Biomarkers, and Gene Expression Related to Inflammation and Lipid in Adults with Metabolic Syndrome

Tehran University of Medical Sciences0 个研究点目标入组 44 人开始时间: 待定最近更新: 2024年1月22日

试验速览

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•Age between 30 and 50 years old
•Body mass index (BMI) ranged from 25 to 35 kg/m2
•The presence of at least three of the five components of the metabolic syndrome according to the ATP III criteria including waist circumference greater than 102 cm in men and 88 cm in women, triglyceride equal to or greater than 150 mg/dL, HDL less than or equal to 40 in men and less than or equal to 50 In women, blood pressure equal to or greater than 130/85 mmHg and blood sugar equal to or greater than 100 mg/dL
•Willingness to participate in the study

•Participate in weight loss programs over the past six months
•Weight change of more than 10% in the last six months
•Professional athletes or changes in the intensity and level of physical activity during the last four weeks
•Pregnant, lactating and postmenopausal women
•Allergy to dairy products and probiotics
•Smoking and alcohol consumption
•Routine consumption of products containing probiotics or synbiotics
•Diagnosed cardiovascular, kidney, gastrointestinal, endocrine, pulmonary, neurological, and autoimmune diseases; diabetes; thyroid dysfunction; cancer; and eating disorders.
•Taking medications that could affect appetite, body weight, and lipid metabolism or have anti-inflammatory effects such as corticosteroids, oral contraceptives, antidepressants and antipsychotics, anti-diabetics, statins, and other lipid-lowering drugs.
•Take antibiotics one month before the study begins
•Uncontrolled blood pressure
•ke probiotics and other dietary supplements within one months before the start of the study

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