The effect of metformin with vitamin E in improving breast pain and fibroadenoma size
Phase 3
Recruiting
- Conditions
- Breast fibroadenoma.Malignant neoplasm of breast
- Registration Number
- IRCT20191104045328N21
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Definitive diagnosis of breast fibroadenoma, unilateral or bilateral fibroadenoma less than 3 cm in size
Consent to participate in the study
aged 18-45
Body mass index above 30
Exclusion Criteria
Suffering from metabolic and endocrinology diseases
Presence of pregnancy and breastfeeding
History of malignant breast masses
Use of anti-diabetic, hypoglycemic and anti-fat drugs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Breast fibroadenoma size. Timepoint: before the start of the study, three months and six months after the start of treatment. Method of measurement: sonography.;Mastalgia. Timepoint: before the start of the study, three months and six months after the start of treatment. Method of measurement: Visual Analogue Scale of pain.
- Secondary Outcome Measures
Name Time Method