Genetic Mechanisms in Human Hypertension RAAS Inhibition Study
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- One type of blood pressure medication will better treat individuals with certain genetic backgrounds.
研究概览
简要总结
The purpose of this study is to develop an approach to provide personalized medicine to individuals who have hypertension (high blood pressure). The investigators plan to use people's genetic characteristics (traits) to determine what medication they should use to lower their blood pressure most effectively. The investigators will give individuals one of two medications to treat hypertension (lisinopril or atenolol). The investigators believe that depending on the individuals genetic background one medication will work better in lowering their blood pressure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female hypertensive participants who were previously studied in SCOR program.
排除标准
- •Taking other medications beside thyroid or estrogen supplements.
研究组 & 干预措施
Lisinopril, Atenolol
干预措施: Lisinopril, Atenolol (Drug)
结局指标
主要结局
One type of blood pressure medication will better treat individuals with certain genetic backgrounds.
时间窗: 16 weeks
次要结局
未报告次要终点
研究者
Gordon H. Williams, MD
Chief, Cardiovascular Endocrinology Section
Brigham and Women's Hospital