The Effect of (L-PRF) Membrane in The Treatment of Gingival Recession
- Conditions
- Localized Gingival Recession
- Interventions
- Procedure: Leukocyte Platelet rich fibrin membrane
- Registration Number
- NCT04224935
- Lead Sponsor
- Ain Shams University
- Brief Summary
evaluation of the use of L-PRF membrane with coronally repositioned flap in treatment of localized gingival recession (Class I \& II) in comparison with the use of connective tissue graft
- Detailed Description
Twenty patients, who are candidates for gingival recession coverage, will participate in this prospective clinical trial.
Group 1(10 patients) :
Coronally repositioned flap will be done and L PRF membrane will be placed into the tissues
Group 2 (Control group)(10 patients) :
Coronally repositioned flap will be done with sub epithelial connective tissue Parameters
* Clinical evaluation of percentage of root coverage and keratinized tissue width
* Esthetic outcome evaluation Will be done using the root coverage esthetic score (Cairo et al. 2009) that include
Both evaluations will be done at 3, 6 and 9 months
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- Systemically free patients (American Society of Anesthesiologists I; ASA I).
- Age range (20 -40) years.
- Good compliance with the plaque control instructions following initial therapy.
- Patients diagnosed with Miller class I or II in anterior and premolar teeth
- Availability for follow up and maintenance program.
- Patient suffering from periodontitis
- Presence of smoking habit.
- Presence of occlusion interference.
- Pregnant and lactating females.
- Vulnerable group of patients (handicapped, mentally retarded and prisoners).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description connective tissue Leukocyte Platelet rich fibrin membrane connective tissue will be used Leukocyte Platelet Rich Fibrin Leukocyte Platelet rich fibrin membrane Leukocyte Platelet Rich Fibrin will be used
- Primary Outcome Measures
Name Time Method recession treatment 9 months 2-Esthetic outcome evaluation was done using Root coverage esthetic score (RES) system ( Cairo et al. 2009) the RES include the following parameters
• Level of the gingival margin (GM):(minimum) Zero points = failure of root coverage (gingival margin apical or equal to the baseline recession); 3 points = partial root coverage;(maximum) 6 points = CRC.
- Secondary Outcome Measures
Name Time Method soft tissue thickness (Volumetric assessment) 9 months Preoperatively a cast was made and scanned. At 9 months after surgical procedure the same procedure was done to determine the soft tissue thickness after the surgery. The difference between the tissue thickness before and after was used to determine the efficacy of the different surgical grafting materials used.
Trial Locations
- Locations (1)
Faculty of Dentistry Ain Shams University
🇪🇬Cairo, Egypt