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Clinical Trials/ACTRN12621001499875
ACTRN12621001499875RecruitingPhase 2

A randomized feasibility study comparing dexmedetomidine with standard of care drug therapy in the management of agitation patients with a palliative diagnosis in a hospice setting.

Dr Lana Ferguson0 sites20 target enrollmentStarted: November 4, 2021Last updated:
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Conditions

Trial Snapshot

Phase
Phase 2
Status
Recruiting
Sponsor
Enrollment
20
Study OverviewStudy DesignEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional
Allocation
Randomised controlled trial
Primary Purpose
Treatment
Masking
Open (masking not used)

Eligibility Criteria

Ages
18 Years to o limit (—)
Sex
All

Inclusion Criteria

  • •Palliative diagnosis with a prognosis of 6 months or less;
  • •Patient has agitation requiring pharmacological management (RASS-PAL greater than or equal to +2);
  • •18 years and over.

Exclusion Criteria

  • •Patients with known AV block in the absence of functioning pacemaker;
  • •Bradycardia (baseline heart rate less than 55 beats per minute);
  • •Patients with end-stage heart failure with documented ejection fraction <20%;
  • •Hypotension (systolic blood pressure < 90mmHg);
  • •Patients with a chronic mental health history who are taking long-term antipsychotic medication.
  • •Non-English speaking

Investigators

Sponsor
Dr Lana Ferguson

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