Comparison of Autologous Quadriceps and Hamstring Tendon Grafts in Anterior Cruciate Ligament Reconstruction

Not Applicable

Recruiting

• Conditions: Anterior Cruciate Ligament Injuries; Athletic Injuries; Tendon Graft; Complications
• Interventions: Procedure: Anterior Cruciate Ligament Reconstruction with Quadriceps Autograft; Procedure: Anterior Cruciate Ligament Reconstruction with Hamstring Autograft

• Registration Number: NCT06617559
• Lead Sponsor: Muzaffer Agir

Brief Summary

With the recent technological advancements, the use of the quadriceps tendon with an all-inside technique has come to the forefront, and large-scale research has focused especially on quadriceps tendon grafts. Clinical study results have reported that the outcomes are similar to those of patellar tendon grafts and either equivalent or superior to hamstring tendon grafts.

The aim of this study is the prospective comparison of the clinical and radiological outcomes of patients who underwent anterior cruciate ligament (ACL) reconstruction with autologous hamstring and quadriceps tendon grafts.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-14
• Status Verified: 2024-09
• Study First Submitted: 2024-09-23
• Study First Submitted QC: 2024-09-26
• Last Update Submitted: 2024-09-26
• Study First Posted: 2024-09-27
• Last Update Posted: 2024-09-27
• Primary Completion: 2025-10
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Elite athletes
• Amateur athletes
• Anterior cruciate ligament injury

Exclusion Criteria

• Revision surgery
• Another ligament injury ( medial collateral ligament, lateral collateral ligament, etc.. )
• > Grade-2 cartilage injury
• Having previously undergone surgery on the same knee
• < 18 years age

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
All-inside Quadriceps Tendon Graft Group	Anterior Cruciate Ligament Reconstruction with Quadriceps Autograft	-
All-inside Hamstring Tendon Graft Group	Anterior Cruciate Ligament Reconstruction with Hamstring Autograft	-

Primary Outcome Measures

Name	Time	Method
Autograft Maturation	12 months	Comparison of different autografts maturation on MRI images. The signal-to-noise quotient formula will be used to assess graft maturation. According to the method described by Chan and Yau, the difference between the signals of the ACL graft and the quadriceps tendon will be used to evaluate maturation by relating it to the background signal.
Stability of Knee	9 months	Lachman test

Secondary Outcome Measures

Name	Time	Method
Range of Motion	6 months	Measurement of knee flexion and extension degrees with a goniometer.
Muscle Strength	9 months	Measurement of quadriceps and hamstring muscle strength with Cybex test

Trial Locations

Locations (1)

Acibadem Fulya Hospital; 🇹🇷 Istanbul, Turkey