Response evaluation after chemoradiation for advanced oropharyngeal cancer using PET-CT and MRI

Completed

• Conditions: oropharynx cancer; throat cancer; 10029107

• Registration Number: NL-OMON37398
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

*Oropharyngeal squamous cell carcinoma
*Initially resectable
*Scheduled for chemoradiation

Exclusion Criteria

*Pregnancy
*Physical condition contra-indication salvage surgery
*Contra-indication for MRI (i.e. claustrofobia)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint is accuracy with which diagnostic tests reduce the number<br /><br>of avoided futile EUAs. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are interobserver agreement, SUV (FDG-PET) and ADC (DW-MRI)<br /><br>thresholds, associated costs and burden of diagnostic procedures and health<br /><br>related quality of life. </p><br>