A controlled clinical trial investigating the impact of point of care testing for ‘atypical’ pneumonia, bordetella pertussis and viral pathogens on patient pathways, antimicrobial consumption and cost-efficiency.
- Conditions
- Rapid PCR-based diagnostic test when placed at the point of careInfections and Infestations
- Registration Number
- ISRCTN10470967
- Lead Sponsor
- King's College Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 2262
1. = 16 years of age
2. Have mental capacity to give written informed consent to participate in the study
3. Have acute upper respiratory tract infection or influenza-like illness +/- lower respiratory tract infection. Symptoms include fever or feeling feverish (chills), cough, sore throat, runny or stuffy nose, muscle-aches or body-aches, headaches, fatigue (tiredness), some people may have vomiting or diarrhoea (though this is more common in children than adults). Please note that not all patients with influenza have fever.
Please note that patients with a clinical or radiological diagnosis of community-acquired lower respiratory tract infection, evidence/suspicion of bacterial infection with common, ‘typical’ respiratory tract pathogens, patients with known or suspected immune suppression, and those with sepsis or severe sepsis are also eligible for inclusion.
1. Those who do NOT meet the inclusion criteria
2. Evidence/suspicion of bacterial infection affecting sites other than the respiratory tract
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Antibiotic use and length of hospital stay
- Secondary Outcome Measures
Name Time Method 1. Turnaround time of tests<br>2. Readmission rate<br>3. Mortality<br>4. Ease of use of Point of Care Test<br>5. Cost benefit