Clinical study on acupuncture intervention of 'Siguan point' on nausea and vomiting induced by high emetic chemotherapy in patients with breast cancer

Phase 1

Recruiting

• Conditions: Chemotherapy-Induced Nausea and Vomiting

• Registration Number: ITMCTR2100004352
• Lead Sponsor: China-Japan Friendship Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients with breast cancer confirmed by pathology and meeting the chemotherapy indications;
2. Patients between 20 and 75 years old;
3. Patients whose chemotherapy regimens are mainly AC regimens or contain platinum;
4. Patients whose expected survival time is more than 6 months;
5. Patients with ECoG score 0-2;
6. The patients who voluntarily participated in the study signed the informed consent.

Exclusion Criteria

1. Patients with severe hepatic and renal insufficiency;
2. Patients with coagulation dysfunction, thrombocytopenia or bleeding related diseases;
3. Patients with refractory vomiting not caused by chemotherapy or existed before chemotherapy;
4. Patients with mental disorders;
5. Patients with hypotension;
6. Patients with edema, infection, ulceration or skin disease at acupuncture site;
7. Patients who feel dizzy, afraid of needling and blood sickness.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in serum 5-HT levels;Degree of nausea and vomiting;TCM Syndrome Points;

Secondary Outcome Measures

Name	Time	Method
Hospital anxiety and depression scale;