Ultrasound Guided Core Biopsy vs Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy
- Conditions
- Focus: Breast Cancer With Axillary Node Metastasis
- Registration Number
- NCT01920139
- Lead Sponsor
- University of Pittsburgh
- Brief Summary
The study was performed to determine if either ultrasound guided core biopsy or fine needle aspiration of an axillary lymph node has superior sensitivity in detecting metastatic carcinoma from the ipsilateral breast.
- Detailed Description
Women with suspected or recently diagnosed breast cancer and ipsilateral abnormal appearing axillary lymph nodes underwent fine needle aspiration immediately followed by core biopsy of the same lymph node.Cytology results from the fine needle aspiration (FNA)and histology from the core biopsy were compared to surgical pathology from axillary node excision to determine if either method of percutaneous node sampling was more sensitive in detecting metastasis. Pain during each procedure was also compared.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 105
- Women with breast cancer and abnormal ipsilateral axillary nodes visible on sonography.
- Inability to understand consent form.
- Emotionally unprepared to discuss possibility of axillary metastasis
- Node not amenable to core biopsy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Fraction of metastatic nodes found at axillary surgery that were identified pre-surgically by FNA vs. core biopsy 1 week to 10 months Results of FNA cytology and core biopsy histology are compared to axillary surgery results.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Magee Womens Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
Magee Womens Hospital🇺🇸Pittsburgh, Pennsylvania, United States