Clinical trial on prevention as well as reduction of chemotherapy-induced neuropathy with acupuncture treatment on the breast cancer patients
- Conditions
- Chemotherapy-induced peripheral neuropathy
- Registration Number
- ITMCTR2200006866
- Lead Sponsor
- Jiangsu Provincial Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- Not specified
(1) Patients with histological diagnosis of stage I-III breast cancer, excluding distant metastases
(2) Patients who plan to receive adjuvant or neoadjuvant chemotherapy (with or without HER-2 targeted therapy) must be enrolled before the second adjuvant chemotherapy.
(3) Over 18 years of age
(4) Sign informed consent
6. No serious organic damage to heart, kidney, liver or brain;
7. Signed the informed consent, participated in and randomly assigned to a study group with no history of substance abuse, and actively cooperated with treatment and follow-up.
(1) Previous CIPN-causing chemotherapy (one dose of chemotherapy allowed).
(2) There were unstable heart disease and myocardial infarction in the first six months
(3) Have a pacemaker or implantable cardioverter defibrillator
(4) Uncontrollable seizures
(5) Prior peripheral neuropathy (PRO-CTCAE CIPN Scale)
(6) Acupuncture within three months before enrollment
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method EORTC QLQ-CIPN20 scale mean change value;
- Secondary Outcome Measures
Name Time Method QLQ-C30 Scale;KPS;NRS Scale;