Healing Touch in Advanced Cervical Cancer Patients: Immune Effects and Mechanisms
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- natural killer cell cytotoxicity
研究概览
简要总结
The purpose of this study is to evaluate the effects of healing touch and relaxation therapy on cervical cancer patients undergoing chemotherapy and radiation treatment.
详细描述
The side effects of chemotherapy and radiation treatment are often severe and can have devastating effects on the mental and physical well-being of cancer patients. This study will determine whether healing touch and relaxation therapy are effective in minimizing the side effects of chemotherapy and radiation treatment in cervical cancer patients.
Participants in this study will receive weekly chemotherapy and daily radiation treatments for 6 weeks. Participants will be randomly assigned to receive either standard care (SC), SC plus relaxation therapy, or SC plus healing touch therapy. The relaxation therapy consists of progressive muscle relaxation and guided imagery. The healing touch therapy involves an energy-based modality in which health care practitioners stimulate the energy fields surrounding the patient. A physician-completed assessment and measures of immune function will be used to assess the well-being and overall quality of life of participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Stage Ib1-IVa cervical cancer
- •Treatment with concurrent chemotherapy and radiation at the University of Iowa Hospitals and Clinics
排除标准
- •Immunosuppressive disorders
- •Use of immunosuppressive medications
- •Transplant recipient
- •Metastatic or recurrent cervical cancer
- •History of any other type of cancer
结局指标
主要结局
natural killer cell cytotoxicity
时间窗: Baseline to week 6
T-cell counts
时间窗: Baseline to week 6
side effects
时间窗: Baseline to week 6
次要结局
- WBC and RBC(Baseline to week 6)
- days of treatment delay(Baseline to week 6)
- salivary cortisol(Baseline to post-treatment)
- distress(Baseline to week 6)