Preventing HIV/Aids in Tx-Resistant Drug-Abusing Youth
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Oregon Research Institute
- Enrollment
- 111
- Locations
- 2
- Primary Endpoint
- Changes in adolescent's substance use.
Study Overview
Brief Summary
This project involves two studies focusing on the engagement and treatment of adolescents diagnosed with substance use disorders. Study 1 will evaluate a promising parent-based engagement intervention, Community Reinforcement Training, designed to facilitate the entry of resistant drug-abusing adolescents in treatment. The approach will be compared with an Engagement As Usual intervention condition. Study 2 involves a controlled clinical trial evaluating the efficacy of an HIV/AIDS prevention intervention embedded in family-based drug abuse treatment for reducing HIV/AIDS risk behaviors and substance use. Adolescents who are successfully engaged in treatment through Study 1 will be randomly assigned to receive either family therapy alone or family therapy with the integrated HIV/AIDS prevention intervention. Both studies are being conducted in Portland, Oregon.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 15 Years to 20 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Parents have an adolescent in the ages of 15-20 years.
- •Have had contact with the adolescent on at least 40% of the past 90 days.
- •Have some knowledge or evidence that the adolescent would meet DSM-IV diagnostic criteria for a substance abuse disorder.
- •Adolescent has explicitly refused to attend any intake or therapy sessions.
- •All parents' efforts to enter adolescent into treatment have failed, despite therapist's assistance.
- •Residence in Portland vicinity.
- •Sufficient residential stability to permit probable contact at follow-up. (e.g. not homeless at time of intake)
Exclusion Criteria
- •Evidence of psychotic or organic state of sufficient severity to interfere with understanding of study instruments and procedures.
- •Adolescent has received residential drug treatment longer than a 2-week period in the past 90 days.
Outcomes
Primary Outcomes
Changes in adolescent's substance use.
Time Frame: 12 months
Secondary Outcomes
- Changes in HIV risk behaviors.(12 months)