The Relationship Between Insulin Resistance and Disease Severity and Duration in Atopic Dermatitis Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Bezmialem Vakif University
- Enrollment
- 32
- Locations
- 1
- Primary Endpoint
- SCORAD index
Study Overview
Brief Summary
The aim of the study is to determine the relationship between insulin resistance and disease duration and severity of atopic dermatitis.
Detailed Description
The aim of the study is to determine the relationship between insulin resistance and disease duration and severity of atopic dermatitis. EASI and SCORAD values and disease duration of atopic dermatitis patients are calculated during the examination. HOMA-IR blood test result is compared with the results.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 2 Years to 80 Years (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Atopic dermatitis patients confirmed by a dermatologist
Exclusion Criteria
- •patients younger than 2 years
- •patients older than 80 years
- •Atopic dermatitis patients without HOMA-IR result
Outcomes
Primary Outcomes
SCORAD index
Time Frame: 12 months
Severity scoring of atopic dermatitis is calculated for each patient in the study. 6 intensity items (erythema, edema/papulation, oozing/crusts, excoriations, lichenification, dryness); 2 subjective symptoms(itch, sleeplessness); body surface area are studied. Max score is 103.
HOMA-IR
Time Frame: 12 months
Patients' blood test show the result of fasting insulin (microU/L) x fasting glucose (mmol/L)/22.5
Duration of the disease
Time Frame: 12 months
The time from the first onset of symptoms of the disease to the present. The relationship between insulin resistance and disease duration is examined
EASI index
Time Frame: 12 months
Eczema Area and Severity Index is calculated for each patient in the study. Body surface area, 4 intensity items(erythema, induration, excoriation, lichenification) are studied. Max score is 72.
Secondary Outcomes
No secondary outcomes reported