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Clinical Trials/NCT04548986
NCT04548986
Completed
Not Applicable

Single-center Prospective Study to Validate the Performance of the Aktiia Optical Blood Pressure Monitoring (OBPM) Device at the Wrist Against Ambulatory Blood Pressure Monitoring (ABPM)

Cyril Pellaton1 site in 1 country63 target enrollmentStarted: August 6, 2020Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
63
Locations
1
Primary Endpoint
Mean error for blood pressure

Overview

Brief Summary

This study aims to assess the performances of optical blood pressure monitoring device, Aktiia.product in the context of cardiac rehabilitation program.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Screening
Masking
None

Eligibility Criteria

Ages
21 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Adult subjects (aged between 21 and 65)
  • Subjects fluent in written and spoken French
  • Subjects enrolled in a 12-weeks cardiac rehabilitation program
  • Subjects agreeing to participate
  • Subjects that have signed the informed consent form

Exclusion Criteria

  • Subjects with tachycardia (heart rate at rest \> 120bpm)
  • Subjects with atrial fibrillation
  • Subjects with severe heart failure (LVEF\<35%)
  • Subjects with severe renal dysfunctions (eGFR \< 30mL/min/1.73 m2)
  • Subjects with pheochromocytoma
  • Subjects with Raynaud's disease
  • Subjects with trembling and shivering
  • Subjects with interarm systolic difference \> 15 mmHg
  • Subjects with interarm diastolic difference \> 10 mmHg
  • Subjects with arm paralysis

Outcomes

Primary Outcomes

Mean error for blood pressure

Time Frame: up to 24 hours

The mean error between the Reference and Aktiia.product for SYS and DIA in mmHg

Mean absolute error for blood pressure

Time Frame: up to 24 hours

The mean absolute error between the Reference (standard ambulatory blood pressure monitor) and Aktiia.product for systolic (SYS) and diastolic (DIA) blood pressure in mmHg

Standard deviation of the error for blood pressure

Time Frame: up to 24 hours

The standard deviation of the error between Reference and Aktiia.product for SYS and DIA in mmHg

Mean absolute error for heart rate

Time Frame: up to 24 hours

The mean absolute error between the Reference (standard ambulatory blood pressure monitor) and Aktiia.product for heart rate in bpm

Mean error for heart rate

Time Frame: up to 24 hours

The mean error between the Reference and Aktiia.product for heart rate in bpm

Standard deviation of the error for heart rate

Time Frame: up to 24 hours

The standard deviation of the error between Reference and Aktiia.product for heart rate in bpm

Secondary Outcomes

  • Assessment of systolic and diastolic blood pressure control during a 12 weeks cardiac rehabilitation program(12 weeks)
  • Evaluation of the impact of ABPM induced stress on BP readings using inferential statistics.(1 week)
  • Evaluation of patient's satisfaction for the two devices through a survey with multiple questions(up to 24 hours)
  • Assessment of the calibration stability of Aktiia OBPM algorithms(12 weeks)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Cyril Pellaton

Cyril Pellaton

Hopital Neuchatelois

Study Sites (1)

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