Development and Research of an Individualized Intelligent Platform for Rehabilitaion in Patients With Parkinson's Disease
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 75
- Locations
- 1
- Primary Endpoint
- mini-BESTest
Study Overview
Brief Summary
The present study aims to compare the clinical efficacy of intelligent POWER therapy, intelligent LSVT-BIG therapy, and the three exercise models currently in clinical use. DCM_IR analysis will also be incorporated into the analysis to develop a personalized and intelligent Parkinson's rehabilitative therapy platform.
Detailed Description
Background:
Parkinson's disease is a progressively degenerative disorder. Patients need early screening, therapeutic intervention, and personalized interaction with outpatient rehabilitative treatment. In the past, it had been difficult to meet these goals. Recent advances in bio-sensors technology has enabled collection of bio-metric data. Models of brainwave analysis have also matured. In addition, our ability to analyze vibrational spectrogram had also greatly improved. How to combine these enabling technologies to meet the needs of Parkinson's patients is an urgent topic of research.
Objective:
The present study aims to compare the clinical efficacy of intelligent POWER therapy, intelligent LSVT-BIG therapy, and the three exercise models currently in clinical use. DCM_IR analysis will also be incorporated into the analysis to develop a personalized and intelligent Parkinson's rehabilitative therapy platform.
Method:
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 40 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •.Parkinson's disease diagnosis, Hoehn-Yahr level I-III
- •.Stable medicine intake for 2 weeks at least
- •.Able to walk independently for 15 meters
- •.Aged 40-85 years old
Exclusion Criteria
- •.Cognition deficits(MMSE score<24)
- •.Combined other neurological disease, such as stork, SCI, and so on.
- •.Pregnant or Breastfeeding
Arms & Interventions
LSVT-BIG
Participants in this group would be treated with LSVT-BIG for three months
Intervention: LSVT-BIG (Other)
POWER
Participants in this group would be treated with POWER for three months
Intervention: POWER (Other)
Traditional rehabilitation
Participants in this group would be treated with traditional exercise rehabilitation for three months
Intervention: Traditional rehabilitation (Other)
Outcomes
Primary Outcomes
mini-BESTest
Time Frame: 15 mins
Mini BESTest assesses dynamic balance, a unidimensinal construct and includes 14 items addressing 4 of the 6 sections of the original BESTest (anticipatory postural adjustments, reactive postural control, sensory orientation, dynamic gait).
Secondary Outcomes
- Unified Parkinson's disease rating scale(15 mins)
- muscle power of lower extremity(5 mins)
- PDQ-39(30 mins)