Racial and Socioeconomic Differences in Chronic Low Back Pain
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.
研究概览
简要总结
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non-specific cLBP that has persisted for at least 3 months and has resulted in pain on at least half the days in the past 6 months.
- •Age 18 - 85; the lower end of this age range was chosen to capture the growing prevalence of young adults with cLBP, and participants over 85 years are increasingly likely to meet one or more
排除标准
- •Participants report ethnic group as non-Hispanic and racial group as either Black/African American or White/Caucasian.
- •Low back pain that is attributable to other factors such as ankylosing spondylitis, infection, malignancy, compression fracture of other trauma.
- •Systemic rheumatic disease/condition (e.g. rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia).
- •Any other chronic pain condition that the participant believes to be more prominent or severe than the low back pain.
- •A history of clinically significant surgery to the low back within the past year.
- •Uncontrolled hypertension (i.e. SBP/DBP of > 150/95), cardiovascular or peripheral arterial disease.
- •Poorly controlled diabetes (HbA1c > 8%).
- •Neurological disease (e.g. Parkinson's, multiple sclerosis, epilepsy).
- •Serious psychiatric disorder requiring hospitalization within the past 12 months or characterized by active suicidal ideation.
- •Diminished cognitive function that would interfere with understanding of study procedures.
结局指标
主要结局
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.
时间窗: two years
Clinical pain severity will be observed through quantitative sensory testing and self-reported questionnaires and surveys.
To elucidate racial group disparities in psychosocial risk factors, among NHBs and NHWs with cLBP.
时间窗: two years
Psychosocial risk factors that will be observed will be greater increases in depressive symptoms, anxiety, and perceived stress, as well as greater social isolation and loneliness through the use of self-reported questionnaires and surveys.
To elucidate racial group disparities in experimental pain sensitivity among NHBs and NHWs with cLBP.
时间窗: two years
Quantitative sensory testing equipment and biological markers assayed via blood samples.
次要结局
未报告次要终点
研究者
Burel Goodin
Prof of Anesthesiology
Washington University School of Medicine