Treatment of iron deficiency anaemia in pregnancy study

Not Applicable

Completed

• Conditions: Iron deficiency anaemia in pregnancy; Haematological Disorders; Iron deficiency anaemia

• Registration Number: ISRCTN13007439
• Lead Sponsor: The Royal Wolverhampton NHS Trust,

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-06-25
• Study Completion: 2020-03-01
• Last Update Posted: 26 September 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 111

Inclusion Criteria

1. Pregnant women (any stage during pregnancy up to 36 weeks) and women in the puerperium (within 6 weeks post-delivery)
2. Anaemia as defined by WHO criteria and described in British Society Haematology (BSH)/ British Committee for standards in Haematology (BCSH) guidelines.
2.1. First trimester < 110g/l
2.2. Second and third trimester < 105g/l
2.3. Puerperium < 100g/l
3. Age: 18-45 years

Exclusion Criteria

1. Presenting at or after 36 weeks
2. Affected by a (major) haemoglobinopathy e.g. B thalassaemia major sickle cell disease
3. Overt clinical signs of sepsis
4. Allergies to iron
5. Hyperemesis Gravidarum / persistent vomiting
6. Inflammatory conditions such as Crohns, ulcerative colitis, Systemic lupus erythematosus, Rheumatoid arthritis.
7. Chronic renal failure

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of pregnant women who meet the criteria for a clinical response, defined as an increase in haemoglobin concentration of 10g/l measured using serum haemoglobin concentration at baseline and 2-4 weeks after the onset of iron therapy.