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The discovery of new biomarkers for the diagnosis of early hepatocellular carcinoma by liquid biopsy

Not Applicable
Recruiting
Conditions
Neoplasms
Registration Number
KCT0007938
Lead Sponsor
Soon Chun Hyang University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
70
Inclusion Criteria

CHB induced LC, HCC(size less than 3cm), more than 19 years old
HCC diagnosed with histology
CHB induced liver cirrhosis
CHB
Normal control

Exclusion Criteria

1.HCV,HIV positive patients
2.Liver transplantation
3.Prior diagnosed with HCC and other malignancy (more than 5 yrs is possible)
4.Steroid or immnosupressed agents(recent 3 month, more than 2 weeks prescription duration)
5.No recent HCC (less than 1 month interval) in CT or MRI in patients with CHB or CHB induced LC

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
quantity and metylation of cell free DNA
Secondary Outcome Measures
NameTimeMethod
tumor marker, clinical indicators
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