Analytical Transversal Study of Cytokines Serum Levels in Chronic Low Back Pain Due to Herniated Disk
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- cytokines levels in patients with chronic low back pain and in healthy subjects
研究概览
简要总结
The purpose of this study is to:
- evaluate if there is an association between elevated levels of cytokines and chronic pain due to herniated disk disease
- measured cytokines levels in chronic low back pain and in healthy subjects.
详细描述
23 patients with at least three months of back pain due to herniated disk disease were selected Diagnosis was confirmed by magnetic resonance imaging (MRI) or computerized tomography (CT) imaging of the spine for all patients. In addition, pain severity had to be ³ 5 points on the Numerical Rating Scale (NRS) ranging from zero (no pain) to 10 (worst imaginable pain).
The exclusion criteria were defined as one or more of the following: psychiatric disorders, systemic or inflammatory disease, history of allergy, presence of motor deficits, history of blood dyscrasia, pregnancy, active infection, tumor, use of analgesic drugs in the week before or inability to come to the hospital for evaluation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •23 patients
- •least three months of back pain due to herniated disk disease
- •pain severity had to be 5 points on the Numerical Rating Scale (NRS)
- •10 healthy volunteers:
- •without previous history of back pain
排除标准
- •One or more of the following:
- •psychiatric disorders
- •systemic or inflammatory disease
- •history of allergy
- •presence of motor deficits
- •history of blood dyscrasia
- •pregnancy
- •active infection, tumor
- •use of analgesic drugs in the week before
- •inability to come to the hospital for evaluation.
结局指标
主要结局
cytokines levels in patients with chronic low back pain and in healthy subjects
时间窗: 30 days after collect
次要结局
未报告次要终点