Evaluation of Clinical Significance and Feasibility of CT Guided Biopsy of Double Site Lesions：A Preliminary Lung Centered Study

Completed

• Conditions: Carcinoma of the Lungs
• Interventions: Diagnostic Test: Double site CT guided needle biopsy

• Registration Number: NCT04960631
• Lead Sponsor: Peking University Third Hospital

Brief Summary

This study aims to explore the clinical significance and feasibility of double site biopsy by analyzing the pathological characteristics and the incidence of main complications of CT guided puncture biopsy of lung and other parts coexisting lesions.

Detailed Description

CT guided biopsy is minimally invasive, accurate and low cost. It is often used as an important diagnostic method when the clinical suspect of malignant disease or the treatment effect of the disease is not good. In patients with suspected malignant lung disease, metastasis of other parts of lung, pulmonary door, mediastinum, bone, and distant soft tissue may be combined at the same time. It is the key link of clinical work to evaluate the nature of these coexisting lesions accurately and choose appropriate treatment methods. At present, there is little clinical study on lung centered double site biopsy. This study aims to explore the clinical significance and feasibility of double site biopsy by analyzing the pathological characteristics and the incidence of main complications of CT guided puncture biopsy of lung and other parts coexisting lesions.

Study Timeline

• Study Start: 2018-03-01
• Primary Completion: 2018-04-30
• Study Completion: 2018-05-31
• Status Verified: 2021-06
• Study First Submitted: 2021-06-29
• Study First Submitted QC: 2021-07-02
• Last Update Submitted: 2021-07-02
• Study First Posted: 2021-07-14
• Last Update Posted: 2021-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 134

Inclusion Criteria

• patients with suspected malignancy
• underwent dual site CT guided biopsy in the Third Hospital of Peking University

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Exclusion Criteria

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Clinical diagnosis of suspected malignant tumor by dual site CT guided needle biopsy	Double site CT guided needle biopsy	-

Primary Outcome Measures

Name	Time	Method
for the combination of two site biopsy approaches 1	up to 2weeks	The incidence of pneumothorax on the surgical side after unilateral lung biopsy
for the combination of two site biopsy approaches 3	up to 2weeks	the incidence of intra tissue hemorrhage after biopsy were statistically analyzed.
for the combination of two site biopsies	up to 2weeks	The incidence of 4 kinds of combined pathological results in different lesion location groups was analyzed.
for the combination of two site biopsy approaches 2	up to 2weeks	the incidence of pneumothorax on the surgical side after bilateral lung biopsy

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China