Artificial Intelligence to Assess the Association Between Facial Characteristics and Coronary Artery Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 6,864
- 试验地点
- 9
- 主要终点
- Sensitivity of diagnostic model
研究概览
简要总结
The purposes of this study are 1) to explore the association between facial characteristics and the increased risk of coronary artery diseases; 2) to evaluate the diagnostic efficacy of appearance factors for coronary artery diseases.
详细描述
Several age-related appearance factors were described associated with increased risk of coronary artery diseases (CAD). However, several limitations made these facial risk factors hard to be utilized in clinical practice, including 1) low prevalence in CAD patients, 2) lack of specific definition, 3) poor reproducibility in artificial recognition.
Thus, the investigators designed a multi-center, cross-sectional study to explore the association between facial characteristics and CAD and evaluate the diagnostic efficacy of appearance factors for CAD. The investigators will recruit patients undergoing coronary angiography or coronary computer tomography angiography. Patients' baseline information and facial images will be collected. First, the investigators will explore the facial factors associated with CAD by using artificial intelligence technology to compare facial photographs between patients with CAD and without CAD. Secondary, the investigators will evaluate the dose-response relationship between facial characteristics and CAD. Third, the investigators will establish a CAD risk model based on facial factors, and evaluate the diagnostic effect of the model.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Undergoing coronary angiography or coronary computer tomography angiography
- •Written informed consent
排除标准
- •Prior percutaneous coronary intervention (PCI)
- •Prior coronary artery bypass graft (CABG)
- •Screening coronary artery disease before treating other heart diseases
- •Without blood biochemistry outcome
- •With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up)
- •Other situations which make patients fail to be photographed
结局指标
主要结局
Sensitivity of diagnostic model
时间窗: at the end of enrollment (6 months)
The sensitivity of coronary artery diagnostic model assessed in model test group
次要结局
- Diagnostic accuracy rate(at the end of enrollment (6 months))
- Specificity of diagnostic model(at the end of enrollment (6 months))
- Positive predictive value (PPV)(at the end of enrollment (6 months))
- Negative predictive value (NPV)(at the end of enrollment (6 months))