Holistic approach of Alzheimer’s disease in Thai people

Not Applicable

Recruiting

• Conditions: Alzheimer’s disease; Whole genome sequencing; Human genome; Transcriptome sequencing

• Registration Number: TCTR20201019003
• Lead Sponsor: Governance

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-19
• Study Completion: 2023-01-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1.Diagnostic of clinical assessment criteria neuropsychiatric tests
2.No psychiatric diseases or using drugs that affect the nervous system
3.Agree to participate in research projects

Exclusion Criteria

1.Physical diseases and/or brain diseases affecting the study. ex. chronic kidney disease, chronic liver disease, diabetes mellitus at HbA1C more than or equal to 7
2.Pregnant or breastfeeding women.
3.Those who can not or do a CT and MRI of the brain.
4.Those in the treatment or monitoring the disease to exposure to radiation.
5.The suspect dementia from other causes ex. depression, ischemic stroke.
6. Those who screened MRI brain found lesions in supcortical white matter more than or equal to 10 mm. or lesions less than 10 mm./More than or equal to 3 lesions.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
genetic code of alzheimer's disease 5 year laboratory test, clinical data,The implementation of Alzheimer's disease in Thai population 5 year Neuropsychiatric test, Laboratory test, Clinical data,Brain function and perform brain mapping. 5 year MRI, Laboratory test, Clinical data,Brain imaging 5 year PET/CT-Scan, Laboratory test, Clinical data,Genetic code of Alzheimer's disease 5 year Next Generation Sequencing Technology, Laboratory test, Clinical data,genetic code of alzheimer's disease 5 year MRI,Linking gut microbiota, Nutritional related to Alzheimer’s disease 5 year Nutritional status, 24-hour dietary recall,determination of physical activity, Laboratory test, Clin,Genetic code of Alzheimer's disease 5 year Whole Genome Sequencing, Laboratory test, Clinical data

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A