Trans Health: Evaluation of Markers of Cardio-metabolic Health and Well-being in Transgender Youth
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Body composition as measured by Dual-energy X-ray absorptiometry (DEXA) in transgender youth compared to age- and BMI-matched controls of both sexes.
研究概览
简要总结
This study plans to learn more about puberty blockers and cross (testosterone and estradiol). There is not much known about how these medications affect hormone levels, heart health and overall general health in young transgender individuals.
详细描述
This study plans to learn more about puberty blockers and cross (testosterone and estradiol). There is not much known about how these medications affect hormone levels, heart health and overall general health in young transgender individuals.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 9 Years 至 21 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Followed in Endocrinology Clinic or Adolescent Medicine Clinic at Children's Hospital Colorado
- •Between age 9 and 21 years (inclusive)
- •Identifies as transgender
- •Has been on pubertal blockade or cross-sex hormones for at least three months.
排除标准
- •Known diabetes
- •Presence of significant medical or psychiatric comorbidities
- •Using hormones not prescribed by a physician
结局指标
主要结局
Body composition as measured by Dual-energy X-ray absorptiometry (DEXA) in transgender youth compared to age- and BMI-matched controls of both sexes.
时间窗: at enrollment
Reproductive hormone concentrations in transgender youth on cross-sex hormones and/or puberty blockers and compared to age-, natal sex- and body mass index (BMI)-matched controls.
时间窗: at enrollment
Markers of cardiometabolic risk in transgender youth on cross-sex hormones and/or puberty blockers and compared to age-, natal sex- and BMI-matched controls
时间窗: at enrollment
Data on quality of life as measured by the Pediatric Quality of Life Inventory (PedsQL) compared to published norms
时间窗: at enrollment
次要结局
未报告次要终点