Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes

Phase 3

Completed

Conditions: Diabetes Mellitus, Type 2

Interventions: Drug: Placebo
Drug: BI 10773
Drug: Sitagliptin 100mg

Registration Number: NCT01289990

Lead Sponsor: Boehringer Ingelheim

Brief Summary: This study will investigate the efficacy and long term safety and tolerability of BI 10773 in type 2 diabetic patients.

Detailed Description: Not available

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 2705

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
BI 10773 low (metformin)	BI 10773	BI 10773 tablets once daily
BI 10773 high (metformin)	BI 10773	BI 10773 tablets once daily
Placebo (pioglitazone)	Placebo	Placebo tablets matching BI 10773 once daily
BI 10773 low (metformin)	Placebo	BI 10773 tablets once daily
BI 10773 low (drug naive)	BI 10773	BI 10773 tablets once daily
BI 10773 low (drug naive)	Placebo	BI 10773 tablets once daily
BI 10773 high (drug naive)	Placebo	BI 10773 tablets once daily
BI 10773 high (drug naive)	BI 10773	BI 10773 tablets once daily
Placebo (drug naive)	Placebo	Placebo tablets matching BI 10773 / Sitagliptin once daily
BI 10773 high (metformin)	Placebo	BI 10773 tablets once daily
Placebo (metformin)	Placebo	Placebo tablets matching BI 10773 once daily
BI 10773 low (metformin+sulfonylurea)	BI 10773	BI 10773 tablets once daily
BI 10773 low (metformin+sulfonylurea)	Placebo	BI 10773 tablets once daily
BI 10773 high (metformin+sulfonylurea)	Placebo	BI 10773 tablets once daily
Placebo (metformin+sulfonylurea)	Placebo	Placebo tablets matching BI 10773
Sitagliptin 100mg (drug naive)	Placebo	Sitagliptin once daily
Sitagliptin 100mg (drug naive)	Sitagliptin 100mg	Sitagliptin once daily
BI 10773 low (pioglitazone)	Placebo	BI 10773 tablets once daily
BI 10773 high (pioglitazone)	Placebo	BI 10773 tablets once daily
BI 10773 high (metformin+sulfonylurea)	BI 10773	BI 10773 tablets once daily
BI 10773 low (pioglitazone)	BI 10773	BI 10773 tablets once daily
BI 10773 high (pioglitazone)	BI 10773	BI 10773 tablets once daily

Primary Outcome Measures

Name	Time	Method
Changes From Baseline in HbA1c (%) After 76 Weeks of Treatment	Baseline and 76 weeks	Change from baseline in HbA1c after 76 weeks
Changes From Baseline in Glycosylated Haemoglobin (HbA1c) (%) After 52 Weeks of Treatment	Baseline and 52 weeks	Change from baseline in HbA1c after 52 weeks

Secondary Outcome Measures

Name	Time	Method
Systolic Blood Pressure: Change From Baseline After 52 Weeks of Treatment	Baseline and 52 weeks	Systolic blood pressure - change from baseline after 52 weeks of treatment
Body Weight (kg) Change From Baseline After 76 Weeks of Treatment	Baseline and 76 weeks	Body Weight (kg) - Change From Baseline After 76 Weeks of Treatment
Waist Circumference (cm) Change From Baseline After 52 Weeks of Treatment	Baseline and 52 weeks	Waist circumference (cm) - change from baseline after 52 weeks of treatment
Waist Circumference (cm) Change From Baseline After 76 Weeks of Treatment	Baseline and 76 weeks	Waist circumference (cm) - change from baseline after 76 weeks of treatment
Diastolic Blood Pressure: Change From Baseline After 76 Weeks of Treatment	Baseline and 76 weeks	Diastolic blood pressure - change from baseline after 76 weeks of treatment
Systolic Blood Pressure: Change From Baseline After 76 Weeks of Treatment	Baseline and 76 weeks	Systolic blood pressure - change from baseline after 76 weeks of treatment
Diastolic Blood Pressure: Change From Baseline After 52 Weeks of Treatment	Baseline and 52 weeks	Diastolic blood pressure - change from baseline after 52 weeks of treatment
Body Weight (kg) Change From Baseline After 52 Weeks of Treatment	Baseline and 52 weeks	Body Weight (kg) - Change From Baseline After 52 Weeks of Treatment
Fasting Plasma Glucose Change From Baseline After 52 Weeks of Treatment	Baseline and 52 weeks	Fasting plasma glucose - change from baseline after 52 weeks of treatment
Fasting Plasma Glucose Change From Baseline After 76 Weeks of Treatment	Baseline and 76 weeks	Fasting plasma glucose - change from baseline after 76 weeks of treatment
HbA1c (%) Changes From Baseline After 76 Weeks of Treatment	Baseline and 76 weeks	Change from baseline in HbA1c (%) after 76 weeks using MMRM approach

Trial Locations

Locations (243): 1245.31.20018 Boehringer Ingelheim Investigational Site
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Victoria, British Columbia, Canada
1245.31.35305 Boehringer Ingelheim Investigational Site
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Co. Galway, Ireland
1245.31.10034 Boehringer Ingelheim Investigational Site
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Rochester, New York, United States
1245.31.10086 Boehringer Ingelheim Investigational Site
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Salisbury, North Carolina, United States
1245.31.20024 Boehringer Ingelheim Investigational Site
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Paradise, Newfoundland and Labrador, Canada
1245.31.32021 Boehringer Ingelheim Investigational Site
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Mouscron, Belgium
1245.31.32018 Boehringer Ingelheim Investigational Site
🇧🇪
Tielt, Belgium
1245.31.32026 Boehringer Ingelheim Investigational Site
🇧🇪
Tremelo, Belgium
1245.31.20032 Boehringer Ingelheim Investigational Site
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Calgary, Alberta, Canada
1245.31.20023 Boehringer Ingelheim Investigational Site
🇨🇦
Edmonton, Alberta, Canada
1245.31.10033 Boehringer Ingelheim Investigational Site
🇺🇸
Chattanooga, Tennessee, United States
1245.31.10158 Boehringer Ingelheim Investigational Site
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Mount Pleasant, South Carolina, United States
1245.31.10015 Boehringer Ingelheim Investigational Site
🇺🇸
Simpsonville, South Carolina, United States
1245.31.10143 Boehringer Ingelheim Investigational Site
🇺🇸
Killeen, Texas, United States
1245.31.20015 Boehringer Ingelheim Investigational Site
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Winnipeg, Manitoba, Canada
1245.31.32023 Boehringer Ingelheim Investigational Site
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Bruxelles, Belgium
1245.31.32024 Boehringer Ingelheim Investigational Site
🇧🇪
Linkebeek, Belgium
1245.31.20003 Boehringer Ingelheim Investigational Site
🇨🇦
Markham, Ontario, Canada
1245.31.32015 Boehringer Ingelheim Investigational Site
🇧🇪
Deurne, Belgium
1245.31.32025 Boehringer Ingelheim Investigational Site
🇧🇪
Gozée, Belgium
1245.31.10112 Boehringer Ingelheim Investigational Site
🇺🇸
Memphis, Tennessee, United States
1245.31.20027 Boehringer Ingelheim Investigational Site
🇨🇦
Laval, Quebec, Canada
1245.31.20006 Boehringer Ingelheim Investigational Site
🇨🇦
Toronto, Ontario, Canada
1245.31.32003 Boehringer Ingelheim Investigational Site
🇧🇪
De Pinte, Belgium
1245.31.32020 Boehringer Ingelheim Investigational Site
🇧🇪
Sint-Gillis-Waas, Belgium
1245.31.20030 Boehringer Ingelheim Investigational Site
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Etobicoke, Ontario, Canada
1245.31.20036 Boehringer Ingelheim Investigational Site
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Sherbrooke, Quebec, Canada
1245.31.32019 Boehringer Ingelheim Investigational Site
🇧🇪
Leopoldsburg, Belgium
1245.31.20034 Boehringer Ingelheim Investigational Site
🇨🇦
Sarnia, Ontario, Canada
1245.31.20009 Boehringer Ingelheim Investigational Site
🇨🇦
Newmarket, Ontario, Canada
1245.31.20019 Boehringer Ingelheim Investigational Site
🇨🇦
Hamilton, Ontario, Canada
1245.31.20035 Boehringer Ingelheim Investigational Site
🇨🇦
Corunna, Ontario, Canada
1245.31.20005 Boehringer Ingelheim Investigational Site
🇨🇦
Strathroy, Ontario, Canada
1245.31.20002 Boehringer Ingelheim Investigational Site
🇨🇦
Toronto, Ontario, Canada
1245.31.91105 Boehringer Ingelheim Investigational Site
🇮🇳
Pune, India
1245.31.35302 Boehringer Ingelheim Investigational Site
🇮🇪
Co. Cork, Ireland
1245.31.35306 Boehringer Ingelheim Investigational Site
🇮🇪
Co. Wexford, Ireland
1245.31.81001 Boehringer Ingelheim Investigational Site
🇯🇵
Chuo-ku, Tokyo, Japan
1245.31.82012 Boehringer Ingelheim Investigational Site
🇰🇷
Anyang, Korea, Republic of
1245.31.82011 Boehringer Ingelheim Investigational Site
🇰🇷
Goyang, Korea, Republic of
1245.31.81007 Boehringer Ingelheim Investigational Site
🇯🇵
Chiyoda-ku, Tokyo, Japan
1245.31.49001 Boehringer Ingelheim Investigational Site
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Dormagen, Germany
1245.31.82001 Boehringer Ingelheim Investigational Site
🇰🇷
Incheon, Korea, Republic of
1245.31.82004 Boehringer Ingelheim Investigational Site
🇰🇷
Pusan, Korea, Republic of
1245.31.35304 Boehringer Ingelheim Investigational Site
🇮🇪
Birr, Co. Offaly, Ireland
1245.31.81002 Boehringer Ingelheim Investigational Site
🇯🇵
Chuo-ku, Tokyo, Japan
1245.31.52002 Boehringer Ingelheim Investigational Site
🇲🇽
Monterrey, Mexico
1245.31.74004 Boehringer Ingelheim Investigational Site
🇸🇰
Presov, Slovakia
1245.31.38001 Boehringer Ingelheim Investigational Site
🇸🇮
Maribor, Slovenia
1245.31.33019 Boehringer Ingelheim Investigational Site
🇫🇷
Strasbourg, France
1245.31.81003 Boehringer Ingelheim Investigational Site
🇯🇵
Minato-ku, Tokyo, Japan
1245.31.52001 Boehringer Ingelheim Investigational Site
🇲🇽
Monterrey, Mexico
1245.31.63002 Boehringer Ingelheim Investigational Site
🇵🇭
Cebu, Philippines
1245.31.81006 Boehringer Ingelheim Investigational Site
🇯🇵
Shinjuku-ku, Tokyo, Japan
1245.31.63003 Boehringer Ingelheim Investigational Site
🇵🇭
Davao City, Philippines
1245.31.82005 Boehringer Ingelheim Investigational Site
🇰🇷
Seoul, Korea, Republic of
1245.31.82014 Boehringer Ingelheim Investigational Site
🇰🇷
Seoul, Korea, Republic of
1245.31.82009 Boehringer Ingelheim Investigational Site
🇰🇷
Ilsan, Korea, Republic of
1245.31.91008 Boehringer Ingelheim Investigational Site
🇮🇳
Bangalore, India
1245.31.35303 Boehringer Ingelheim Investigational Site
🇮🇪
Co. Wexford, Ireland
1245.31.90003 Boehringer Ingelheim Investigational Site
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Erzurum, Turkey
1245.31.81005 Boehringer Ingelheim Investigational Site
🇯🇵
Ebetsu, Hokkaido, Japan
1245.31.81012 Boehringer Ingelheim Investigational Site
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Urasoe, Okinawa, Japan
1245.31.81008 Boehringer Ingelheim Investigational Site
🇯🇵
Shinjuku-ku, Tokyo, Japan
1245.31.90004 Boehringer Ingelheim Investigational Site
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Izmir, Turkey
1245.31.52003 Boehringer Ingelheim Investigational Site
🇲🇽
Guadalajara, Mexico
1245.31.63001 Boehringer Ingelheim Investigational Site
🇵🇭
Manila, Philippines
1245.31.63005 Boehringer Ingelheim Investigational Site
🇵🇭
Manila, Philippines
1245.31.90001 Boehringer Ingelheim Investigational Site
🇹🇷
Gaziantep, Turkey
1245.31.75003 Boehringer Ingelheim Investigational Site
🇺🇦
Vinnytsya, Ukraine
1245.31.90002 Boehringer Ingelheim Investigational Site
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Istanbul, Turkey
1245.31.75006 Boehringer Ingelheim Investigational Site
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Lviv, Ukraine
1245.31.75004 Boehringer Ingelheim Investigational Site
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Vinnitsa, Ukraine
1245.31.88008 Boehringer Ingelheim Investigational Site
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Taoyuan County, Taiwan
1245.31.75001 Boehringer Ingelheim Investigational Site
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Kharkiv, Ukraine
1245.31.32016 Boehringer Ingelheim Investigational Site
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Deurne, Belgium
1245.31.86035 Boehringer Ingelheim Investigational Site
🇨🇳
Beijing, China
1245.31.86001 Boehringer Ingelheim Investigational Site
🇨🇳
Guangzhou, China
1245.31.86003 Boehringer Ingelheim Investigational Site
🇨🇳
Guangzhou, China
1245.31.86052 Boehringer Ingelheim Investigational Site
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Guangzhou, China
1245.31.86012 Boehringer Ingelheim Investigational Site
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Guiyang, China
1245.31.86020 Boehringer Ingelheim Investigational Site
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Hangzhou, China
1245.31.86055 Boehringer Ingelheim Investigational Site
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Nan Ning, China
1245.31.86039 Boehringer Ingelheim Investigational Site
🇨🇳
Shanghai, China
1245.31.10108 Boehringer Ingelheim Investigational Site
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Phoenix, Arizona, United States
1245.31.10001 Boehringer Ingelheim Investigational Site
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Chicago, Illinois, United States
1245.31.10156 Boehringer Ingelheim Investigational Site
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Houston, Texas, United States
1245.31.10155 Boehringer Ingelheim Investigational Site
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San Antonio, Texas, United States
1245.31.10119 Boehringer Ingelheim Investigational Site
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Cincinnati, Ohio, United States
1245.31.10045 Boehringer Ingelheim Investigational Site
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Cincinnati, Ohio, United States
1245.31.10145 Boehringer Ingelheim Investigational Site
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Birmingham, Alabama, United States
1245.31.90006 Boehringer Ingelheim Investigational Site
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Istanbul, Turkey
1245.31.81004 Boehringer Ingelheim Investigational Site
🇯🇵
Kamakura, Kanagawa, Japan
1245.31.81010 Boehringer Ingelheim Investigational Site
🇯🇵
Ube, Yamaguchi, Japan
1245.31.81013 Boehringer Ingelheim Investigational Site
🇯🇵
Urasoe, Okinawa, Japan
1245.31.81009 Boehringer Ingelheim Investigational Site
🇯🇵
Suita, Osaka, Japan
1245.31.82006 Boehringer Ingelheim Investigational Site
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Jeonju, Korea, Republic of
1245.31.82003 Boehringer Ingelheim Investigational Site
🇰🇷
Wonju, Korea, Republic of
1245.31.82008 Boehringer Ingelheim Investigational Site
🇰🇷
Seoul, Korea, Republic of
1245.31.82010 Boehringer Ingelheim Investigational Site
🇰🇷
Seoul, Korea, Republic of
1245.31.86049 Boehringer Ingelheim Investigational Site
🇨🇳
Jinan, China
1245.31.10162 Boehringer Ingelheim Investigational Site
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Glendale, Arizona, United States
1245.31.10046 Boehringer Ingelheim Investigational Site
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Tempe, Arizona, United States
1245.31.10154 Boehringer Ingelheim Investigational Site
🇺🇸
Chino, California, United States
1245.31.10127 Boehringer Ingelheim Investigational Site
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Waterbury, Connecticut, United States
1245.31.10085 Boehringer Ingelheim Investigational Site
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Plantation, Florida, United States
1245.31.10137 Boehringer Ingelheim Investigational Site
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Clearwater, Florida, United States
1245.31.10006 Boehringer Ingelheim Investigational Site
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Miami, Florida, United States
1245.31.10077 Boehringer Ingelheim Investigational Site
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Perry, Georgia, United States
1245.31.10159 Boehringer Ingelheim Investigational Site
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Des Moines, Iowa, United States
1245.31.10014 Boehringer Ingelheim Investigational Site
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Dubuque, Iowa, United States
1245.31.10117 Boehringer Ingelheim Investigational Site
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Arkansas City, Kansas, United States
1245.31.10149 Boehringer Ingelheim Investigational Site
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Rancho Cucamonga, California, United States
1245.31.10157 Boehringer Ingelheim Investigational Site
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Newton, Kansas, United States
1245.31.10123 Boehringer Ingelheim Investigational Site
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Smithtown, New York, United States
1245.31.10071 Boehringer Ingelheim Investigational Site
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Asheboro, North Carolina, United States
1245.31.32008 Boehringer Ingelheim Investigational Site
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Bruxelles, Belgium
1245.31.20057 Boehringer Ingelheim Investigational Site
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Brampton, Ontario, Canada
1245.31.20008 Boehringer Ingelheim Investigational Site
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St. John's, Newfoundland and Labrador, Canada
1245.31.20026 Boehringer Ingelheim Investigational Site
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Halifax, Nova Scotia, Canada
1245.31.20060 Boehringer Ingelheim Investigational Site
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London, Ontario, Canada
1245.31.20029 Boehringer Ingelheim Investigational Site
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London, Ontario, Canada
1245.31.20040 Boehringer Ingelheim Investigational Site
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Oakville, Ontario, Canada
1245.31.20007 Boehringer Ingelheim Investigational Site
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Montague, Prince Edward Island, Canada
1245.31.20058 Boehringer Ingelheim Investigational Site
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St-Romuald, Quebec, Canada
1245.31.20025 Boehringer Ingelheim Investigational Site
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Montreal, Quebec, Canada
1245.31.20021 Boehringer Ingelheim Investigational Site
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Trois Rivieres, Quebec, Canada
1245.31.20038 Boehringer Ingelheim Investigational Site
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Ville Saint-Laurent, Quebec, Canada
1245.31.86008 Boehringer Ingelheim Investigational Site
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Beijing, China
1245.31.86007 Boehringer Ingelheim Investigational Site
🇨🇳
Beijing, China
1245.31.20041 Boehringer Ingelheim Investigational Site
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Saskatoon, Saskatchewan, Canada
1245.31.86033 Boehringer Ingelheim Investigational Site
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Beijing, China
1245.31.86031 Boehringer Ingelheim Investigational Site
🇨🇳
Beijing, China
1245.31.86034 Boehringer Ingelheim Investigational Site
🇨🇳
Beijing, China
1245.31.86032 Boehringer Ingelheim Investigational Site
🇨🇳
Beijing, China
1245.31.86058 Boehringer Ingelheim Investigational Site
🇨🇳
Chongqing, China
1245.31.86038 Boehringer Ingelheim Investigational Site
🇨🇳
Dalian, China
1245.31.86037 Boehringer Ingelheim Investigational Site
🇨🇳
Haerbin, China
1245.31.86053 Boehringer Ingelheim Investigational Site
🇨🇳
Jinan, China
1245.31.86019 Boehringer Ingelheim Investigational Site
🇨🇳
Nanchang, China
1245.31.86018 Boehringer Ingelheim Investigational Site
🇨🇳
Jingzhou, China
1245.31.86056 Boehringer Ingelheim Investigational Site
🇨🇳
Nan Ning, China
1245.31.86016 Boehringer Ingelheim Investigational Site
🇨🇳
QingDao, China
1245.31.86045 Boehringer Ingelheim Investigational Site
🇨🇳
Shijiazhuang, China
1245.31.86054 Boehringer Ingelheim Investigational Site
🇨🇳
Shantou, China
1245.31.86057 Boehringer Ingelheim Investigational Site
🇨🇳
Shenyang, China
1245.31.86017 Boehringer Ingelheim Investigational Site
🇨🇳
Shiyan, China
1245.31.86013 Boehringer Ingelheim Investigational Site
🇨🇳
Suzhou, China
1245.31.86011 Boehringer Ingelheim Investigational Site
🇨🇳
Xi'An, China
1245.31.86015 Boehringer Ingelheim Investigational Site
🇨🇳
Taiyuan, China
1245.31.86036 Boehringer Ingelheim Investigational Site
🇨🇳
Tianjin, China
1245.31.86041 Boehringer Ingelheim Investigational Site
🇨🇳
Xi'An, China
1245.31.33008 Boehringer Ingelheim Investigational Site
🇫🇷
Bersée, France
1245.31.86014 Boehringer Ingelheim Investigational Site
🇨🇳
Xiamen, China
1245.31.33020 Boehringer Ingelheim Investigational Site
🇫🇷
Bischheim, France
1245.31.33002 Boehringer Ingelheim Investigational Site
🇫🇷
Bondy Cedex, France
1245.31.33016 Boehringer Ingelheim Investigational Site
🇫🇷
Bruay La Buissiere, France
1245.31.33001 Boehringer Ingelheim Investigational Site
🇫🇷
Corbeil Essonnes, France
1245.31.33003 Boehringer Ingelheim Investigational Site
🇫🇷
La Rochelle Cedex 1, France
1245.31.33045 Boehringer Ingelheim Investigational Site
🇫🇷
Marseille, France
1245.31.33004 Boehringer Ingelheim Investigational Site
🇫🇷
Narbonne Cedex, France
1245.31.33012 Boehringer Ingelheim Investigational Site
🇫🇷
Schiltigheim, France
1245.31.33013 Boehringer Ingelheim Investigational Site
🇫🇷
Strasbourg, France
1245.31.33007 Boehringer Ingelheim Investigational Site
🇫🇷
Vieux Condé, France
1245.31.33018 Boehringer Ingelheim Investigational Site
🇫🇷
Wattrelos, France
1245.31.49013 Boehringer Ingelheim Investigational Site
🇩🇪
Dresden, Germany
1245.31.49016 Boehringer Ingelheim Investigational Site
🇩🇪
Düsseldorf, Germany
1245.31.49009 Boehringer Ingelheim Investigational Site
🇩🇪
Flörsheim, Germany
1245.31.49019 Boehringer Ingelheim Investigational Site
🇩🇪
Haag, Germany
1245.31.49015 Boehringer Ingelheim Investigational Site
🇩🇪
Frankfurt, Germany
1245.31.49004 Boehringer Ingelheim Investigational Site
🇩🇪
Hatten, Germany
1245.31.49020 Boehringer Ingelheim Investigational Site
🇩🇪
Hohenmölsen, Germany
1245.31.49002 Boehringer Ingelheim Investigational Site
🇩🇪
Neuwied, Germany
1245.31.49007 Boehringer Ingelheim Investigational Site
🇩🇪
Künzing, Germany
1245.31.49010 Boehringer Ingelheim Investigational Site
🇩🇪
Rednitzhembach, Germany
1245.31.49005 Boehringer Ingelheim Investigational Site
🇩🇪
Saarbrücken, Germany
1245.31.49022 Boehringer Ingelheim Investigational Site
🇩🇪
Schauenburg, Germany
1245.31.49017 Boehringer Ingelheim Investigational Site
🇩🇪
St. Ingbert/Oberwürzbach, Germany
1245.31.49011 Boehringer Ingelheim Investigational Site
🇩🇪
Rehlingen-Siersburg, Germany
1245.31.49006 Boehringer Ingelheim Investigational Site
🇩🇪
Rehburg-Loccum, Germany
1245.31.49003 Boehringer Ingelheim Investigational Site
🇩🇪
Unterschneidheim, Germany
1245.31.91006 Boehringer Ingelheim Investigational Site
🇮🇳
Bangalore, India
1245.31.30004 Boehringer Ingelheim Investigational Site
🇬🇷
Thessaloniki, Greece
1245.31.91005 Boehringer Ingelheim Investigational Site
🇮🇳
Bangalore, India
1245.31.91003 Boehringer Ingelheim Investigational Site
🇮🇳
Belgaum, India
1245.31.91004 Boehringer Ingelheim Investigational Site
🇮🇳
Chennai, India
1245.31.91009 Boehringer Ingelheim Investigational Site
🇮🇳
Chennai, India
1245.31.91103 Boehringer Ingelheim Investigational Site
🇮🇳
Maharashtra, India
1245.31.91001 Boehringer Ingelheim Investigational Site
🇮🇳
Coimbatore, India
1245.31.91015 Boehringer Ingelheim Investigational Site
🇮🇳
Gulbarga, India
1245.31.91101 Boehringer Ingelheim Investigational Site
🇮🇳
Coimbatore, India
1245.31.91012 Boehringer Ingelheim Investigational Site
🇮🇳
New Delhi, India
1245.31.91014 Boehringer Ingelheim Investigational Site
🇮🇳
Pune, India
1245.31.74003 Boehringer Ingelheim Investigational Site
🇸🇰
Trebisov, Slovakia
1245.31.41003 Boehringer Ingelheim Investigational Site
🇨🇭
Rorschach, Switzerland
1245.31.88006 Boehringer Ingelheim Investigational Site
🇨🇳
Taipei, Taiwan
1245.31.88014 Boehringer Ingelheim Investigational Site
🇨🇳
Tainan, Taiwan
1245.31.10038 Boehringer Ingelheim Investigational Site
🇺🇸
Northglenn, Colorado, United States
1245.31.10059 Boehringer Ingelheim Investigational Site
🇺🇸
New Hyde Park, New York, United States
1245.31.10151 Boehringer Ingelheim Investigational Site
🇺🇸
Hurst, Texas, United States
1245.31.10131 Boehringer Ingelheim Investigational Site
🇺🇸
West Hills, California, United States
1245.31.10124 Boehringer Ingelheim Investigational Site
🇺🇸
Mesa, Arizona, United States
1245.31.10133 Boehringer Ingelheim Investigational Site
🇺🇸
Jupiter, Florida, United States
1245.31.82007 Boehringer Ingelheim Investigational Site
🇰🇷
Seoul, Korea, Republic of
1245.31.10080 Boehringer Ingelheim Investigational Site
🇺🇸
Decatur, Georgia, United States
1245.31.33010 Boehringer Ingelheim Investigational Site
🇫🇷
Croix, France
1245.31.10146 Boehringer Ingelheim Investigational Site
🇺🇸
Louisville, Kentucky, United States
1245.31.82002 Boehringer Ingelheim Investigational Site
🇰🇷
Suwon, Korea, Republic of
1245.31.10003 Boehringer Ingelheim Investigational Site
🇺🇸
Dearborn, Michigan, United States
1245.31.20022 Boehringer Ingelheim Investigational Site
🇨🇦
Brampton, Ontario, Canada
1245.31.10130 Boehringer Ingelheim Investigational Site
🇺🇸
Gallipolis, Ohio, United States
1245.31.10129 Boehringer Ingelheim Investigational Site
🇺🇸
Carlisle, Ohio, United States
1245.31.33009 Boehringer Ingelheim Investigational Site
🇫🇷
Hautmont, France
1245.31.49008 Boehringer Ingelheim Investigational Site
🇩🇪
Nürnberg, Germany
1245.31.20028 Boehringer Ingelheim Investigational Site
🇨🇦
Vancouver, British Columbia, Canada
1245.31.63004 Boehringer Ingelheim Investigational Site
🇵🇭
Manila, Philippines
1245.31.74002 Boehringer Ingelheim Investigational Site
🇸🇰
Lucenec, Slovakia
1245.31.74014 Boehringer Ingelheim Investigational Site
🇸🇰
Nove Zamky, Slovakia
1245.31.74001 Boehringer Ingelheim Investigational Site
🇸🇰
Povazska Bystrica, Slovakia
1245.31.38003 Boehringer Ingelheim Investigational Site
🇸🇮
Celje, Slovenia
1245.31.88011 Boehringer Ingelheim Investigational Site
🇨🇳
Kaohsiung, Taiwan
1245.31.88013 Kaohsiung Medical University Chung-Ho Memorial Hospital
🇨🇳
Kaohsiung, Taiwan
1245.31.20012 Boehringer Ingelheim Investigational Site
🇨🇦
Moncton, New Brunswick, Canada
1245.31.20033 Boehringer Ingelheim Investigational Site
🇨🇦
Victoria, British Columbia, Canada
1245.31.52004 Boehringer Ingelheim Investigational Site
🇲🇽
Guadalajara, Mexico
1245.31.88009 Boehringer Ingelheim Investigational Site
🇨🇳
Taichung, Taiwan
1245.31.91007 Boehringer Ingelheim Investigational Site
🇮🇳
Mumbai, Maharastra, India
1245.31.20011 Boehringer Ingelheim Investigational Site
🇨🇦
Chilliwack, British Columbia, Canada
1245.31.91010 Boehringer Ingelheim Investigational Site
🇮🇳
Nagpur, India
1245.31.74006 Boehringer Ingelheim Investigational Site
🇸🇰
Nitra, Slovakia
1245.31.20016 Boehringer Ingelheim Investigational Site
🇨🇦
Mount Pearl, Newfoundland and Labrador, Canada
1245.31.88021 Boehringer Ingelheim Investigational Site
🇨🇳
Taipei, Taiwan
1245.31.91104 Boehringer Ingelheim Investigational Site
🇮🇳
Indore, India
1245.31.91002 Boehringer Ingelheim Investigational Site
🇮🇳
Mumbai, India
1245.31.74005 Boehringer Ingelheim Investigational Site
🇸🇰
Bratislava, Slovakia
1245.31.38002 Boehringer Ingelheim Investigational Site
🇸🇮
Koper, Slovenia
1245.31.41004 Boehringer Ingelheim Investigational Site
🇨🇭
Lugano, Switzerland
1245.31.88010 Boehringer Ingelheim Investigational Site
🇨🇳
Kaohsiung, Taiwan
1245.31.88012 Boehringer Ingelheim Investigational Site
🇨🇳
Kaohsiung, Taiwan
1245.31.75002 Boehringer Ingelheim Investigational Site
🇺🇦
Dnepropetrovsk, Ukraine
1245.31.20017 Boehringer Ingelheim Investigational Site
🇨🇦
London, Ontario, Canada
1245.31.86042 Boehringer Ingelheim Investigational Site
🇨🇳
Nanjing, China
1245.31.86043 Boehringer Ingelheim Investigational Site
🇨🇳
Nanjing, China

Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes

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