A food supplement and cosmetic product treatment based on a new hyaluronic acid for anti-aging effects on the skin of adult females
- Conditions
- Skin ageing and its effects on skin hydration, elasticity/firmness and profilometrySkin and Connective Tissue Diseases
- Registration Number
- ISRCTN18340451
- Lead Sponsor
- Complife Italia Srl
- Brief Summary
2022 Results article in https://doi.org/10.3390/cosmetics9030054 (added 24/08/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 75
1. Good general health
2. Females of caucasian ethnicity
3. Photoype I to IV
4. Age between 35 and 70 years old
5. Mild/moderate signs of ageing (mild/moderate Crow’s feet wrinkles and mild/moderate face slackness)
6. Subjects who have not been recently involved in any other similar study
7. Willingness to use for face care only the creams that will be consigned at the beginning of the study
8. Willingness to submit before and after pictures
9. Willingness to use during all the study period only the products to be tested
10. Willingness not to use similar products that could interfere with the product to be tested
11. Willingness to not vary the normal daily routine (i.e. lifestyle, physical activity, etc.)
12. Subject is under effective contraception (oral/not oral); not expected to be changed during the trial
13. Subject aware of the study procedures and having signed an informed consent form
14. Subjects who accept not to expose themselves in an intensive way to UV rays during the whole study duration
1. Subjects who do not meet the inclusion criteria
2. Pregnant/breastfeeding female or who have planned pregnancy during the study period
3. Positive history for atopy or hypersensitive skin
4. Subjects under systemically pharmacological treatment
5. Subjects under locally pharmacological treatment on the skin area monitored during the test
6. Subjects with congenital or acquired immunodeficiency
7. Subjects under treatment with food supplements which could interfere with the functionality of the product under study
8. Subjects which show other skin alterations on the monitored area
9. Subjects considered as not adequate to participate in the study by the investigator
10. Subjects with known or suspected sensitization to one or more test formulation ingredients
11. Adult protected by law (under control or hospitalized in public or private institutions for reasons other than research, or incarcerated)
12. Subjects not able to communicate or cooperate with the investigator for problems related to language, mental retardation or impaired brain function
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method