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Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques

Completed
Conditions
Melanoma
Interventions
Other: Dermatology patients
Registration Number
NCT02393001
Lead Sponsor
University of Florida
Brief Summary

The purpose of this research study is to determine if a very sensitive chemistry lab analyzer can be used to smell a skin cancer (like melanoma) similar to some dogs.

Detailed Description

Types of skin cancer, like melanoma, are likely to spread and are becoming increasingly common. At this time, healthcare providers look at patient's skin and remove a sample of suspicious areas of the skin (biopsy) to test for cancer.

This research study will inspect cotton and cloth swabs of normal skin and suspicious areas of the skin that are going to be biopsied just before the biopsy. The swabs will be looked at with a very sensitive chemistry lab analyzer to see if the lab analyzer can confirm conventional lab test findings.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • 18 years of age or older
  • Seen at the dermatology clinic & determined to need a skin biopsy of a suspicious lesion
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Exclusion Criteria
  • < 18 years of age
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Dermatology patientsDermatology patientsPatients seen in the dermatology clinic with suspicious skin lesion to be biopsied will have 4 skin swabs, 2 of the skin lesion and 2 of an area of unafflicted skin.
Primary Outcome Measures
NameTimeMethod
Compare the off line spectral analyses of saline and alcohol skin swabs of normal control, melanoma negative and melanoma positive skin biopsies.1 day

Determine if the melanomas have unique identifying spectra that might be applied to noninvasive melanoma skin cancer screening in lieu of taking a biopsy

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UF Health

🇺🇸

Gainesville, Florida, United States

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