Ayurvedic Management of Rheumatoid Arthritis

Not yet recruiting

Conditions: Rheumatoid arthritis without rheumatoid factor,

Registration Number: CTRI/2020/04/024674

Lead Sponsor: Dr Ramyashree Nagendra

Brief Summary: Rheumatoid Arthritis is one of the common autoimmune diseases affecting 0.8 - 1% of adult population in society. It is the most common form of chronic inflammatory arthritis and often results in joint damage and physical disability. Treatment given in contemporary science are DMARD, NSAID, glucocorticoids which results in many complications on long term use like nausea, diarrhoea, vomiting, stomatitis, mood swings etc:-. Hence effective management is to be explored. Simhanada Guggulu which is proven to have effective results in management of Rheumatoid arthritis is taken as controlled group. Its efficacy is compared with Prasarini Sandhanam which is having drugs like Gandha prasarini, lacuna, panchakola and guda. This new formulation is taken for trial group and is expected to have better results due to its anti arthritic and anti inflammatory properties of drugs.

1. To evaluate effect of prasarini sandhanam in management of Amavata w.s.r to Rheumatoid Arthritis

2. To re-evaluate effect of Simhanada Guggulu in management of amavata w.s.r to Rheumatoid Arthritis

3. To compare the efficacy of Prasarini Sandhanam and Simhanada Guggulu in management of amavata w.s.r to Rheumatoid Arthritis.

Null Hypothesis H0 - Efficacy of Prasarini Sandhanam is equal to efficacy of Simhanada Guggulu in management of Amavata w.s.r to Rheumatoid Arthritis

Research Hypothesis H1 - Efficacy of Prasarini Sandhanam is not equal to efficacy of Simhanada Guggulu in management of Amavata w.s.r to Rheumatoid Arthritis

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Willing to give informed consent for research 2.
Subjects who satisfy 4 criteria out of 7 of ARA 3.
Subjects with classical signs and symptoms of Amavata.

Exclusion Criteria

Subjects suffering from Rheumatoid arthritis secondary to any systemic diseases 2.
Patients on any other medications like DMARD, NSAID, Corticosteroids 3.
Patients having complications like swan neck deformity, ulnar deviation and any other diseases which interfere with the course of disease and treatment will be excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in General Functional Capacity	On 45th day the assessment will be done

Secondary Outcome Measures

Name	Time	Method
To elicit the Quality of Life in patients with Amavata w.s.r to Rheumatoid Arthritis	15th, 30th, 45th day

Trial Locations

Locations (1): Sri Sri College of Ayurvedic Science and Research Hospital
🇮🇳
Bangalore, KARNATAKA, India
Sri Sri College of Ayurvedic Science and Research Hospital
🇮🇳Bangalore, KARNATAKA, India
Dr Ramyashee Nagendra
Principal investigator
9663732231
ramyashreenagendra@gmail.com