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临床试验/NCT03839030
NCT03839030已完成不适用

Development and Implementation of Mindfulness-Based Health Promotion Program for Educators (MBHP - Educa): Evaluation of Cognitive Functions and Epigenetic Modifications.

Marcelo Demarzo, MD, PhD1 个研究点 分布在 1 个国家目标入组 146 人开始时间: 2018年3月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
146
试验地点
1
主要终点
Morningness-eveningness questionnaire - sum *Range 16 to 86 *higher scorer - more morningness type

研究概览

简要总结

In the last few decades, the world has seen a significant increase in the occurrence of occupational diseases related to Burnout Syndrome (professional exhaustion) and stress in educators. These disorders affect mental health and teaching activity. In this way, they need to develop socio-emotional skills to cope with the psychosocial stressors related to the school environment. Currently, mindfulness-based therapies have been recommended to help educators acquire emotional self-control, and to improve self-esteem, metacognition, attention, resilience and affectivity, in addition to better the social skills needed in the school milieu. The main objective of the proposed research project is to elaborate a program of Mindfulness-Based Health Promotion - educators (MBHP - educa) to be applied to a population of Brazilian public school educators. The efficacy of the program will be evaluated by cognitive testing. Blood tests for the above-mentioned stress-related molecules will be performed. The goal of developing the MBHP - educa Program is to promote and ameliorate the health care of public school teachers. Developing such a research proposal will contribute to debate and implement public health policies focussed on promoting the health of public school teachers in Brazil.

详细描述

In the last few decades, the world has seen a significant increase in the occurrence of occupational diseases related to Burnout Syndrome (professional exhaustion) and stress in educators. These disorders affect mental health and teaching activity. In this way, they need to develop socio-emotional skills to cope with the psychosocial stressors related to the school environment. Currently, mindfulness-based therapies have been recommended to help educators acquire emotional self-control, and to improve self-esteem, metacognition, attention, resilience and affectivity, in addition to better the social skills needed in the school milieu. A few published studies indicate that mindfulness practices also reduce some inflammation- and stress- related molecules such as cortisol, receptor-interacting serine/threonine kinase 2 (RIPK2), cyclooxygenase 2 (COX2), interleukin 6 (IL-6), tumor necrosis factor-α (TNF-α) and epigenetic-regulation related histone deacetilases (HDAC). These indicator molecules can be measured in blood. The World Health Organisation (WHO-2013) recommends the worldwide implementation of strategies for the promotion of mental health, which are particularly aimed at preventing occupational diseases. The main objective of the proposed research project is to elaborate a program of Mindfulness-Based Health Promotion - educators (MBHP - educa) to be applied to a population of Brazilian public school educators. The efficacy of the program will be evaluated by cognitive testing. Blood tests for the above-mentioned stress-related molecules will be performed. The goal of developing the MBHP - educa Program is to promote and ameliorate the health care of public school teachers. Developing such a research proposal will contribute to debate and implement public health policies focussed on promoting the health of public school teachers in Brazil.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Participant)

入排标准

年龄范围
23 Years 至 65 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Brazilian male or female aged between 23 and 65 years and (2) currently working in the classroom

排除标准

  • (1) the presence of medical conditions or medications use that might affect inflammatory pathways; (2) report of an infectious condition in the last 15 days before collecting a blood sample; (3) active psychiatric and/or clinical comorbidities potentially life-threatening such as psychosis or suicidal ideation; and (4) had previously practiced or currently practicing meditation, yoga or Tai-Chi

结局指标

主要结局

Morningness-eveningness questionnaire - sum *Range 16 to 86 *higher scorer - more morningness type

时间窗: Pre-test, Post-test and follow-up (12 months)

To evaluate person's circadian rhythm (biological clock) (sum of all responses)

World Health Organization Quality of Life-BREF (WHOQOL-BREF)

时间窗: Pre-test, Post-test and follow-up (12 months)

To evaluate quality of life through five subscales: physical domain - mean of responses psychological domain - mean of responses relationships domain - mean of responses environment domain - mean of responses quality of life and perception of life - mean of responses \*each question response range one to five points Higher scores - Better Quality of Life

Pittsburgh Sleep Quality Index

时间窗: Pre-test, Post-test and follow-up (12 months)

To evaluate the Sleep Quality - sum of responses score \*each questions have a specific conversion to range zero to six Higher scores - better sleep quality

次要结局

  • Glutathione metabolism from blood samples(Pre-test, Post-test and follow-up (12 months))
  • Connor-Davidson Resilience Rating Scale(Pre-test, Post-test and follow-up (12 months))
  • Perceived Stress Scale (PSS-10)(Pre-test, Post-test and follow-up (12 months))
  • Determination of cytokine levels in serum samples.(Pre-test, Post-test and follow-up (12 months))
  • Positive and Negative Affect Schedule (PANAS)(Pre-test, Post-test and follow-up (12 months))

研究者

发起方
Marcelo Demarzo, MD, PhD
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Marcelo Demarzo, MD, PhD

Principal Investigator

Centro Mente Aberta de Mindfulness

研究点 (1)

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