How does local anesthetic airway topicalisation, for awake fiberbreoptic intubation (AFOI), affect patient reaction time?
Phase 4
- Conditions
- psychometric effect of lignocaineAnaesthesiology - Anaesthetics
- Registration Number
- ACTRN12610000459022
- Lead Sponsor
- Fremantle Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
voluntary participants in an awake fibre optic course
Exclusion Criteria
1. Known intolerance or allergy to any study drug. (Lidocaine)
2. Active psychosis or history of schizophrenia
3. Pregnancy
4. Severe heart disease, liver disease, diabetes or asthma.
5. Epilepsy
6. History of epistaxis or nasal problems
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Psychometric test pre and post exposure.<br>(Composite Primary Outcome)<br><br>(1)Complex Reaction time test: Reaction time measured to the identification of a simple object.<br>Example: Picture of a dog with the word DOG next to it. True/False option with the reaction time to answer masured. <br><br>(2)Balance test scored to 10<br>stand with feet together =2<br>arms at 90 deg from side =2 <br>bend one knee to 90 deg = 2<br>look up =2<br>close eyes =2<br><br>Loss of 1 point for loss of balance with correction<br>Loss of 2 points with loss of ballance without correction[*pre exposure for baseline<br>*post exposure immediately and at 60min (correlates with maximum plasma level)]
- Secondary Outcome Measures
Name Time Method relation of plasme lignocaine concentration to psychometric outcomes[pre exposure and at 60 min]