The Effect of Body Weight Management and Cognitive Exercise Therapy Approach on Psoriatic Arthritis Symptoms
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Weight Loss
研究概览
简要总结
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. This study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach (BETY-Bilişsel Egzersiz Terapi Yöntemi) interventions on symptoms. Accordingly, 45 overweight/obese subjects with PSA aged 20-65 years will divide into "diet", "diet+bety", and "control" groups. Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at the end of the study.
详细描述
Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. The present study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach interventions on symptoms.
- Fourt-five overweight/obese subjects with PSA aged 20-65 years will divide into diet (n=15), diet+bety (n=15), and control (n=15) groups.
- Individually diet programs will be applied according to the metabolic, biochemical, and physical activity status of the subjects prepared by a registered dietitian.
- BETY exercise training will be given by a registered physiotherapist.
- The subjects will be followed for 12 weeks.
- Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at study completion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •overweight/obese
- •diagnosed with PSA
排除标准
- •pregnancy or lactation
研究组 & 干预措施
diet group
weight loss diet intervention for 12 weeks
干预措施: diet and biopsychosocial exercise intervention (Behavioral)
diet+bety group
weight loss diet intervention for 12 weeks and exercise-based biopsychosocial approach (Cognitive Exercise Therapy Approach-BETY) intervention for 12 weeks
干预措施: diet and biopsychosocial exercise intervention (Behavioral)
control group
no intervention, control
结局指标
主要结局
Weight Loss
时间窗: At the end of 3 months
BMI (kilogram/metre2(kg/m2))
DAPSA score
时间窗: At the end of 3 months
The score ranges from 0 to 50 points, with increased score reflect more discomfort
次要结局
- Quality of Life Score(At the end of 3 months)
研究者
Sumeyra Oteles
Clinical Researcher of the Hacettepe University
Hacettepe University