Comparing Cardiovascular Effects of 1:100,000 and 1:200,000 Epinephrine Solutions

Phase 4

Completed

• Conditions: Cardiovascular Response to Epinephrine

• Registration Number: NCT02735018
• Lead Sponsor: Rio de Janeiro State University

Brief Summary

The study aim to evaluate systemic response of patients when 2 different concentrations of Epinephrine are injected during inferior alveolar nerve block for wisdom teeth extraction.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-12
• Primary Completion: 2015-03
• Study Completion: 2015-03
• Study First Submitted: 2016-03-18
• Status Verified: 2016-04
• Study First Submitted QC: 2016-04-06
• Last Update Submitted: 2016-04-06
• Study First Posted: 2016-04-12
• Last Update Posted: 2016-04-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Class I patients according to the American Society of Anesthesiology (ASA),
• Indication for third molars extraction,
• Similar degree of complexity, according to the classification of Pell and Gregory.

Exclusion Criteria

• Patients with systemic conditions,
• Patients with known allergy to any component of the anesthetic solution.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Bleeding, evaluated by the surgeon as either: 1) normal or 2) excessive	20 minutes
Blood pressure	20 minutes
Pain, evaluated using a visual analogue scale	After procedure, about 1 hour
Arterial oxygen saturation, measured with a pulse oximeter device	20 minutes
Heart rate	20 minutes