A clinical trial to study the effectiveness of low dose antibiotic treatment and placebo for prevention of urinary infection in children with vesicoureteric reflux
Phase 4
Recruiting
- Conditions
- Health Condition 1: null- Urinary tract infections in vesicoureteric reflux patients
- Registration Number
- CTRI/2012/02/002462
- Lead Sponsor
- ICMR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 192
Inclusion Criteria
Children between 1-14 years of age and of either sex who are diagnosed to have primary VUR on micturating cystourethrogram will be recruited.
Exclusion Criteria
1.Patients below 1 year of age
2.Patients with unilateral or bilateral severe(grade V)
3.VUR secondary to urinary tract obstruction including posterior urethral valves, neurogenic bladder and primary megaureter
4.Patients with symptoms of voiding dysfunction
5.Patients with history of drug sensitivity to sulphonamide
6.Immunocompromised patients or those receiving prophylactic cotrimoxazole for
other reasons
7. S.Creatinine > 1.5 mg/dl
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method