Modulation of Painful Perception
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 4
- 主要终点
- Intensity of the perceived pain assessed by the volunteer by a analog scale (VAS) at each thermal stimulation.
研究概览
简要总结
The objective of the study is to evaluate in healthy volunteers, the influence of empathy on pain perception.
It is widely accepted in the clinical management that the feeling of listening to the patients' pain would have a favorable influence on the pain, and conversely, the lack of listening would be aggravating.
In this study, the volunteer will receive painful thermal stimuli in empathetic context (l, empathetic or non-empathetic) Two situations will oppose, one where the examiner neglect or minimize the suffering of the voluntary and the other or the contrary, the subject will receive empathy.
The first part of the project is to verify that the pain is influenced by the empathetic context. The second part will be conducted functional MRI, which should isolate the brain regions affected by other people's empathy for pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Right handed
排除标准
- •Pregnant or lactating women,
- •Against-indications to MRI
- •Drug intake of less than 12 hours,
- •Neurological history or deficits, psychiatric, auditory or visual.
- •Decline to participate
研究组 & 干预措施
healthy volunteers
干预措施: thermal stimulation delivered by a thermode. (Device)
healthy volunteers
干预措施: functional MRI (Other)
结局指标
主要结局
Intensity of the perceived pain assessed by the volunteer by a analog scale (VAS) at each thermal stimulation.
时间窗: Day 0
次要结局
- blood-oxygen-level dependent (MRI)(Day 0)